Evidence map›Paper›PMID 40232577›Full record

ArticleEuropean journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology2025

Performance of Molecular Culture ID in diagnosis of bacterial pericarditis.

Martine P Bos, Maria Miguélez Sánchez, Lauren Remijas, Robin van Houdt, Edgar J G Peters, Andries E Budding

Abstract readEvaluation Study
PubMed Publisher
In one paragraph

Article in European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Diagnostic performance of broad-range PCR in bacterial peritonitis.Frontiers in cellular and infection microbiology · 2025
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Martine P BosInbiome, Science Park 106, Amsterdam, 1098 XG, The Netherlands. martine.bos@inbiome.com.ORCID http://orcid.org/0000-0002-4005-7680
Maria Miguélez SánchezInbiome, Science Park 106, Amsterdam, 1098 XG, The Netherlands.
Lauren RemijasInbiome, Science Park 106, Amsterdam, 1098 XG, The Netherlands.
Robin van HoudtAmsterdam UMC Location Vrije Universiteit Amsterdam, Medical Microbiology and Infection Prevention, Amsterdam, The Netherlands.
Edgar J G PetersInfectious Diseases, and, Amsterdam Infection & Immunity, Infectious Diseases, and, Amsterdam Movement Sciences, Rehabilitation and Development, Amsterdam UMC, Location Vrije Universiteit Amsterdam, Amsterdam, The Netherlands.
Andries E BuddingInbiome, Science Park 106, Amsterdam, 1098 XG, The Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bacterial pericarditis is a serious condition for which diagnosis relies on culture of the pericardial fluid. Culture often remains negative in cases of fastidious organisms or prior antibiotic treatment. To alleviate this issue, we developed Molecular Culture ID (MC-ID), a PCR-based pan-bacterial assay, approved according to the European In Vitro Diagnostic Regulation (IVDR), that identifies bacteria to the species level. Here, we evaluate the diagnostic accuracy of this test on a uniquely large sample set of 42 pericardial effusions. MC-ID identified 11 positive samples whereas culture detected only 7, demonstrating the ability of MC-ID to diagnose bacterial pericarditis.

Indexed as

BacteriaBacterial InfectionsBacteriological TechniquesMolecular Diagnostic TechniquesPericarditisPolymerase Chain ReactionFemaleHumansPericardial FluidSensitivity and Specificity

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.