Evidence map›Paper›PMID 40232527›Full record

ReviewCurrent gastroenterology reports2025

The Neuroimmune Axis in Gastrointestinal Disorders - An Underrecognized Problem.

Laura A Pace, Niwen Kong, Mohamed I Itani, James Hemp

Erratum issuedAbstract readReview
PubMed Publisher
In one paragraph

Review in Current gastroenterology reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Laura A PaceDivision of Gastroenterology and Hepatology, Department of Medicine, Stanford University, Stanford, CA, USA. lapace@stanford.edu.
Niwen KongDivision of Gastroenterology and Hepatology, Department of Medicine, Stanford University, Stanford, CA, USA.
Mohamed I ItaniDivision of Neurology and Neurological Sciences, Department of Medicine, Stanford University, Stanford, CA, USA.
James Hempmeliora.bio, Palo Alto, CA, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewWe present an introduction to the neuroimmune axis with a focus on the gastrointestinal system, its role in numerous chronic multisystem disorders, and emerging tools and therapies to diagnose and treat these conditions. RECENT

findingsThere have recently been tremendous breakthroughs in our understanding of how the nervous, immune, and endocrine systems, as well as the extracellular matrix and microbiota, interact within the gastrointestinal system to modulate health and disease.

Indexed as

Gastrointestinal DiseasesGastrointestinal TractNeuroimmunomodulationGastrointestinal MicrobiomeHumans

Identifiers

PMID40232527

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.