ReviewPediatric surgery international2025
Colorectal cancer in children: an evaluation of the existing literature based on the 11-year experience of a single center.
Review in Pediatric surgery international, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeChildren's risk of developing colorectal cancer (CRC) is relatively low. In this report, we present our experience with CRC in the pediatric age group, together with an extensive review of the literature.
methodsBetween the years 2013 and 2024, a total of five patients diagnosed with CRC underwent treatment at the Department of Pediatric Surgery in our tertiary hospital. A retrospective evaluation was conducted on patients' charts, encompassing demographics, admission symptoms, patient and family histories, laboratory and radiologic findings, operative and pathology reports, genetic and molecular study results, treatment protocols, and follow-up data.
resultsThere were three males and two females, with a mean age of 13.5 ± 2.5 years. The primary sites were the sigmoid and rectosigmoid. Two patients were diagnosed with mucinous adenocarcinoma based on histopathological examination. Among the three remaining patients, one presented with signet ring cells, one displayed moderately differentiated adenocarcinoma characteristics, and one exhibited well-differentiated adenocarcinoma characteristics. At the time of the most recent follow-up, two patients have demonstrated survival.
conclusionThe two main factors contributing to poor survival in pediatric CRC were concluded to be at an advanced stage during diagnosis and having an aggressive histologic subtype. Including CRC in the preliminary diagnosis list is essential for an early diagnosis in the pediatric age group.
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