Evidence map›Paper›PMID 40232330›Full record

ReviewTechniques in coloproctology2025

Current practice and innovations in diagnosing perianal fistulizing Crohn's disease (pfCD): a narrative review.

E Anand, T Pelly, S Joshi, E Shakweh, L N Hanna, A Hart, P Tozer, P Lung

Abstract readReview
In one paragraph

Review in Techniques in coloproctology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Perianal fistulizing Crohn's disease: Clinical practice update from Colitis and Crohn's Foundation (India).Indian journal of gastroenterology : official journal of the Indian Society of Gastroenterology · 2026
    Guideline
  2. Review
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  6. Observational
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

E AnandSt Mark's The National Bowel Hospital, Central Middlesex, Acton Lane, London, UK. era24@ic.ac.uk.
T PellyImperial College London, London, UK.
S JoshiSt Mark's The National Bowel Hospital, Central Middlesex, Acton Lane, London, UK.
E ShakwehSt Mark's The National Bowel Hospital, Central Middlesex, Acton Lane, London, UK.
L N HannaSt Mark's The National Bowel Hospital, Central Middlesex, Acton Lane, London, UK.
A HartSt Mark's The National Bowel Hospital, Central Middlesex, Acton Lane, London, UK.
P TozerSt Mark's The National Bowel Hospital, Central Middlesex, Acton Lane, London, UK.
P LungImperial College London, London, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Perianal fistulizing Crohn's disease (pfCD) represents a severe manifestation of Crohn's disease (CD) that often leads to significant morbidity. Clinical examination alone of perianal fistulae is unlikely to be sufficient in the context of complex pfCD, as patients are likely to have complex disease and are more likely to experience complications, treatment failure, and recurrent disease. Furthermore, the relapsing-remitting nature of Crohn's disease and our limited understanding of the pathogenesis of this potentially destructive disease necessitate regular examination and radiological assessment, often in the form of magnetic resonance imaging (MRI). Recent advancements in diagnostic techniques have enhanced the accuracy and timeliness of pfCD diagnosis, facilitating better patient outcomes. A growing appreciation of isolated perianal Crohn's disease has prompted a recent attempt to develop consensus recommendations on diagnosing and treating this group of patients who would previously not have been offered CD medications. This narrative review aims to summarize current practice and the latest developments in the diagnosis of pfCD, highlighting: 1. Clinical examination and assessment tools 2. Current imaging practices 3. Innovations in imaging and biomarkers 4. The diagnosis of isolated perianal Crohn's disease.

Indexed as

Crohn DiseaseRectal FistulaHumansMagnetic Resonance ImagingDiagnosisFistulaPerianal Crohn’s diseaseRadiology

Identifiers

PMID40232330
PMCPMC12000175

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.