Evidence map›Paper›PMID 40232315›Full record

ArticleJournal of cancer research and clinical oncology2025

Comparing postoperative pain control after modified radical mastectomy: a pilot study of ultra-sound guided erector spinae plane block vs intraoperative tramadol administration in oncology patients.

Ana Cvetković, Marković Ivan, Žegarac Milan, Marko Jevrić, Zoran Bukumiric, Mirčić Dijana, Andrej Jokić, Badnjarević Damjana, Marko Buta

Abstract readComparative Study
In one paragraph

Article in Journal of cancer research and clinical oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ana CvetkovićDepartment of Anesthesia and Intensive Care Unit, Clinic of Surgical Oncology, Institute for Oncology and Radiology of Serbia, 14 Pasterova Street, Belgrade, Serbia. anadjurdjic@yahoo.com.
Marković IvanClinic of Surgical Oncology, Institute for Oncology and Radiology of Serbia, Belgrade, Serbia.
Žegarac MilanClinic of Surgical Oncology, Institute for Oncology and Radiology of Serbia, Belgrade, Serbia.
Marko JevrićClinic of Surgical Oncology, Institute for Oncology and Radiology of Serbia, Belgrade, Serbia.
Zoran BukumiricSchool of Medicine, University of Begrade, Belgrade, Serbia.
Mirčić DijanaDepartment of Anesthesia and Intensive Care Unit, Clinic of Surgical Oncology, Institute for Oncology and Radiology of Serbia, 14 Pasterova Street, Belgrade, Serbia.
Andrej JokićDepartment of Anesthesia and Intensive Care Unit, Clinic of Surgical Oncology, Institute for Oncology and Radiology of Serbia, 14 Pasterova Street, Belgrade, Serbia.
Badnjarević DamjanaDepartment of Anesthesia and Intensive Care Unit, Clinic of Surgical Oncology, Institute for Oncology and Radiology of Serbia, 14 Pasterova Street, Belgrade, Serbia.
Marko ButaClinic of Surgical Oncology, Institute for Oncology and Radiology of Serbia, Belgrade, Serbia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study aimed to compare the effectiveness of ultrasound-guided erector spinae plane block (ESPB) with intraoperative Tramadol for postoperative pain management after modified radical mastectomy (MRM). The primary focus was on pain intensity within the first 24 h, while secondary outcomes included the need for rescue analgesia, nausea, vomiting, and patient satisfaction.

methodsIn this retrospective cohort study, 49 female patients (ASA I-II, aged 30-80) who underwent MRM from 2021 to 2023 were analyzed. Patients were divided into two groups: one receiving ESPB preoperatively (25 patients) and the other receiving Tramadol during surgery (24 patients). Pain levels were measured using the Numeric Rating Scale (NRS), and data on rescue analgesia, vital signs, nausea, vomiting, and patient satisfaction were collected.

resultsThe ESPB group reported significantly lower pain levels during the first six postoperative hours (NRS scores of 0 vs. 3; p = 0.005), along with a reduced need for rescue analgesia (88% vs. 54.2%; p = 0.010). Moreover, patient satisfaction was higher in the ESPB group (64% vs. 37.5%; p = 0.03). The intraoperative heart rate was also lower in the ESPB group (65.3 vs. 72.0 bpm; p = 0.030). No significant differences were found in nausea, vomiting, or length of hospital stay.

conclusionOverall, ESPB demonstrates superior early postoperative pain control and improved patient satisfaction compared to Tramadol. Further studies are needed to confirm these findings.

Indexed as

Analgesics, OpioidBreast NeoplasmsMastectomy, Modified RadicalNerve BlockPostoperative PainTramadolAdultAgedAged, 80 and overFemaleHumansMiddle AgedPain ManagementPain MeasurementPatient SatisfactionPilot ProjectsAnalgesics, OpioidTramadolESPBMRMPlane blockTramadol

Identifiers

PMID40232315
PMCPMC12000122

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.