Evidence map›Paper›PMID 40231625›Full record

ArticleGut microbes2025

Urease in acetogenic

Isaac J Firth, Marissa A R Sim, Bradley G Fitzgerald, Ailish E Moore, Christian R Pittao, Connor Gianetto-Hill, Samantha Hess, Autumn R Sweeney, Emma Allen-Vercoe, Matthew T Sorbara

Abstract read
In one paragraph

Article in Gut microbes, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Gut Microbial Topology and Metabolic Signatures Associated With Colorectal Neoplasia.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  3. Article
  4. Oxygen Tolerance Domestication ofMicroorganisms · 2026
    Article
  5. Article
  6. Host-microbiome mutualism drives urea carbon salvage and acetogenesis during hibernation.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
  7. Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Isaac J FirthDepartment of Molecular and Cellular Biology, University of Guelph, Guelph, Canada.ORCID 0000-0002-7588-9049
Marissa A R SimDepartment of Molecular and Cellular Biology, University of Guelph, Guelph, Canada.ORCID 0000-0003-2043-1820
Bradley G FitzgeraldDepartment of Molecular and Cellular Biology, University of Guelph, Guelph, Canada.
Ailish E MooreDepartment of Molecular and Cellular Biology, University of Guelph, Guelph, Canada.
Christian R PittaoDepartment of Molecular and Cellular Biology, University of Guelph, Guelph, Canada.
Connor Gianetto-HillDepartment of Molecular and Cellular Biology, University of Guelph, Guelph, Canada.
Samantha HessDepartment of Molecular and Cellular Biology, University of Guelph, Guelph, Canada.
Autumn R SweeneyDepartment of Molecular and Cellular Biology, University of Guelph, Guelph, Canada.
Emma Allen-VercoeDepartment of Molecular and Cellular Biology, University of Guelph, Guelph, Canada.
Matthew T SorbaraDepartment of Molecular and Cellular Biology, University of Guelph, Guelph, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The gut microbiota produces short-chain fatty acids (SCFA) and acidifies the proximal colon which inhibits enteric pathogens. However, for many microbiota constituents, how they themselves resist these stresses is unknown. The anaerobic

Indexed as

Bacterial ProteinsCarbonEubacterialesFatty Acids, VolatileUreaUreaseAnimalsColonGastrointestinal MicrobiomeHumansHydrogen-Ion ConcentrationMiceBacterial ProteinsCarbonFatty Acids, VolatileUreaUreaseacetateacetogenesisacidificationAnaerostipesBlautiabutyratecross-feedingLachnospiraceaemicrobiotashort-chain fatty acidsureaurea-derived acetate productionUrease

Identifiers

PMID40231625
PMCPMC12001548

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.