ReviewHistopathology2025
Data set for reporting paediatric renal tumours: recommendations from the international collaboration on cancer reporting (ICCR).
Review in Histopathology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Review
- Tumor-Associated Macrophage Polarization in Wilms' Tumor After Neoadjuvant Chemotherapy.Cancers · 2026Article
- Updated favourable-histology Wilms tumour risk stratification: rationale for future Children's Oncology Group clinical trials.Nature reviews. Urology · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Tumours arising within the developing kidney of children vary widely in their histological appearance and outcome; optimal therapy requires accurate classification and staging. The two major paediatric cooperative groups provide different therapeutic protocols based on different staging and classification, initially developed to serve patients in North America and Europe, but also used in many other parts/regions of the world. The International Collaboration on Cancer Reporting (ICCR) has developed a structure whereby such complex information may be harmonised, and able to be applied to patients globally. An international expert panel consisting of paediatric pathologists and oncologists produced a set of items critical to cancer reporting and subjected these to review and discussion using the structured processes provided by the ICCR. A formal ICCR structure was assembled, and consensus surrounding elements and their application to different therapeutic protocols was developed. The data set underwent open international consultation. This resulted in the first international data set for Wilms tumour (WT) and other paediatric renal tumours, provided herein. The use of ICCR methods enables a full understanding of highly complex and often overlapping reporting elements by international experts, and the potential of developing a set of commonly applied data elements that are fully defined. This sets the groundwork for future consolidation of definitions and harmonisation of therapies for WT and other paediatric renal tumour patients. It also allows institutions outside the major paediatric cooperative groups to provide therapy based on known elements.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.