Evidence map›Paper›PMID 40231251›Full record

ArticleFrontiers in oncology2025

Diagnostic challenges of primary central nervous system histiocytic sarcoma: case report and literature review.

Na Liang, Changxian Chen, Dan Yuan, Qiang Xu, Yali Zhan, Yi Zhao, Di Wu, Cheng Yang, Chunming Li

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Na Liang *Department of Pathology, School of Basic Medicine, Zunyi Medical University, Zunyi, China.
Changxian Chen *Department of Pathology, School of Basic Medicine, Zunyi Medical University, Zunyi, China.
Dan YuanDepartment of Pathology, School of Basic Medicine, Zunyi Medical University, Zunyi, China.
Qiang XuDepartment of Urology, the Second Affiliated Hospital of Zunyi Medical University, Zunyi, China.
Yali ZhanDepartment of Pathology, School of Basic Medicine, Zunyi Medical University, Zunyi, China.
Yi ZhaoThe First Clinical College of Zunyi Medical University, Zunyi, China.
Di WuSchool of Forensic Medicine, Zunyi Medical University, Zunyi, China.
Cheng YangThe First Clinical College of Zunyi Medical University, Zunyi, China.
Chunming LiDepartment of Pathology, School of Basic Medicine, Zunyi Medical University, Zunyi, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Histiocytic sarcoma (HS) is a rare malignant tumor that primarily affects the lymph nodes, intestines, skin, and soft tissues. Primary central nervous system histiocytic sarcoma (PCNSHS) is even rarer. We present the case of a 50-year-old Asian male with PCNSHS who was hospitalized after experiencing intermittent headaches and slurred speech for a week. During surgery, both tumor cells and purulent material were observed, and the diagnosis of PCNSHS was ultimately confirmed by immunohistochemistry. Furthermore, we conducted a literature review from 1952 to the present, screening and analyzing 49 related cases across 41 publications.

Indexed as

case reportdiagnosis and differential diagnosishistiocytic sarcomaimmunohistochemistryprimary central nervous system

Identifiers

PMID40231251
PMCPMC11994660

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.