Evidence map›Paper›PMID 40231188›Full record

ArticleAJOG global reports2025

Exercise during pregnancy (frequency, intensity, type, time, volume): birth outcomes in women at risk of hypertensive disorders of pregnancy.

Alex Claiborne, Breanna Wisseman, Kara Kern, Dylan Steen, Filip Jevtovic, Samantha Mcdonald, Cody Strom, Edward Newton, James Devente, Steven Mouro and 6 more

Abstract read
In one paragraph

Article in AJOG global reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Exercise during pregnancy: increased oxygen uptake and metabolic demand.Journal of applied physiology (Bethesda, Md. : 1985) · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Alex ClaiborneDepartment of Kinesiology, East Carolina University (ECU), Greenville, NC (Claiborne, Wisseman, Kern, Steen, Jevtovic, and May).
Breanna WissemanDepartment of Kinesiology, East Carolina University (ECU), Greenville, NC (Claiborne, Wisseman, Kern, Steen, Jevtovic, and May).
Kara KernDepartment of Kinesiology, East Carolina University (ECU), Greenville, NC (Claiborne, Wisseman, Kern, Steen, Jevtovic, and May).
Dylan SteenDepartment of Kinesiology, East Carolina University (ECU), Greenville, NC (Claiborne, Wisseman, Kern, Steen, Jevtovic, and May).
Filip JevtovicDepartment of Kinesiology, East Carolina University (ECU), Greenville, NC (Claiborne, Wisseman, Kern, Steen, Jevtovic, and May).
Samantha McdonaldSchool of Kinesiology and Recreation, Illinois State University, Normal, IL (Mcdonald).
Cody StromDepartment of Kinesiology and Sport, University of Southern Indiana, Evansville, IN (Strom).
Edward NewtonDepartment of Obstetrics & Gynecology, ECU, Greenville, NC (Newton, Devente, Mouro, Whiteside, Muhammad, and May).
James DeventeDepartment of Obstetrics & Gynecology, ECU, Greenville, NC (Newton, Devente, Mouro, Whiteside, Muhammad, and May).
Steven MouroDepartment of Obstetrics & Gynecology, ECU, Greenville, NC (Newton, Devente, Mouro, Whiteside, Muhammad, and May).
James WhitesideDepartment of Obstetrics & Gynecology, ECU, Greenville, NC (Newton, Devente, Mouro, Whiteside, Muhammad, and May).
Jacqui MuhammadDepartment of Obstetrics & Gynecology, ECU, Greenville, NC (Newton, Devente, Mouro, Whiteside, Muhammad, and May).
David CollierDepartment of Pediatrics, ECU, Greenville, NC (Collier and Kuehn).
Devon KuehnDepartment of Pediatrics, ECU, Greenville, NC (Collier and Kuehn).
George A KelleyDepartment of Epidemiology & Biostatistics, West Virginia University, Morgantown, WV (Kelley).
Linda E MayDepartment of Kinesiology, East Carolina University (ECU), Greenville, NC (Claiborne, Wisseman, Kern, Steen, Jevtovic, and May).

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Hypertensive disorders of pregnancy (HDP) hold negative health implications for mothers and offspring. While the beneficial influence of prenatal exercise on reducing HDP risk has been previously shown, there is a lack of specific information on the effect on birth outcomes in at-risk women, and in-depth analysis of appropriate exercise dose is lacking. Objective: We aimed to elucidate the effects of exercise training FITT-V (frequency, intensity, type, time, volume) on hypertension and birth outcomes in pregnant women. Study Design: This study is a retrospective, secondary analysis of pooled data from three blinded, prospective, randomized controlled trials. Women at risk of HDP (11 control, 27 exercise) were identified from the population and monitored in supervised exercise sessions throughout pregnancy. Upon delivery, birth measures were obtained. Pearson correlations and stepwise regressions determined associations. Tests for outcomes between exercise types were completed using one-way ANOVA. Results: Women at risk of HDP with higher total exercise volume trended lower systolic blood pressure during pregnancy ( Conclusion: The current findings add to a body of literature showing the beneficial influence of exercise during pregnancy on HDP risk, and importantly the effect on exposed offspring. Prenatal exercise improved birth outcomes in women with higher HDP risk in a dose-dependent manner, whereby higher exercise volume and duration are associated with improvements in birth outcomes.

Indexed as

birth measuresdose-responseexerciseFITT-Vhypertensive disorders of pregnancypregnancy

Identifiers

PMID40231188
PMCPMC11994316

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.