ArticleJournal of clinical and experimental dentistry2025
Effect of Matrix Metalloproteinase Inhibitors on the Dentin Bond Strength and Durability of a Two-Step Universal Adhesive System.
Article in Journal of clinical and experimental dentistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
1 citing paper in PubMed.
- Bond strength and interfacial stability of a universal adhesive to alendronate-treated dentin.Scientific reports · 2026Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: The aim of this study was to investigate the effects of using two types of matrix metalloproteinase inhibitors (MMPI) on the dentin bond strength and durability of a two-step universal adhesive (G2-BOND Universal Adhesive). Material and Methods: This study was conducted on 24 extracted molars, resulting in 144 samples. The occlusal surface of the teeth was cut perpendicularly to the longitudinal axis to expose the dentin. The samples were divided into 6 groups: Group 1 (Control, etch-and-rinse (ER)): bonding in the ER mode without MMPI; Group 2: bonding in the ER mode with chlorhexidine (CHX); Group 3: bonding in the ER mode with benzalkonium chloride (BAC); Group 4 (Control, Self-etch (SE)): bonding in the SE mode without MMPI; Group 5: bonding in the SE mode with CHX; Group 6: bonding in the SE mode with BAC. The entire dentin surface was restored with composite resin. Each group was further divided into two subgroups and either thermocycled for 500 or 10,000 cycles. The samples were cut into cylinders with a one square millimeter cross-sectional area and tested for microtensile bond strength (µTBS). Data was analyzed using 3-Way ANOVA and Games-Howell tests ( Results: There was a statistically significant difference in the mean µTBS based on the type of MMPI, aging method, and etching strategy. The mean µTBS in the Control group was significantly lower than in the CHX and BAC groups ( Conclusions: The µTBS to dentin decreases after aging. However, the use of MMPI preserves bond strength to some extent in comparison to control groups after aging.
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Registered trials
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