Evidence map›Paper›PMID 40231021›Full record

ArticleARYA atherosclerosis2022

Effect of Black Cumin Ethanolic Extract Administration to Superoxide Dismutase and Malondialdehyde in Inhibiting Endothelial Dysfunction in Cigarette Exposed Rats.

Meity Ardiana, Budi Pikir, Anwar Santoso, I Gde Suryawan, Hanestya Hermawan, Dita Rachmi, Primasitha Harsoyo

Abstract read
In one paragraph

Article in ARYA atherosclerosis, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Meity ArdianaAirlangga University, Surabaya, Indonesia.
Budi PikirAirlangga University, Surabaya, Indonesia.
Anwar SantosoIndonesia University, Jawa Barat, Indonesia.
I Gde SuryawanAirlangga University, Surabaya, Indonesia.
Hanestya HermawanAirlangga University, Surabaya, Indonesia.
Dita RachmiAirlangga University, Surabaya, Indonesia.
Primasitha HarsoyoAirlangga University, Surabaya, Indonesia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOxidative stress caused by various components in cigarette smoke can induce endothelial dysfunction. Black cumin (

methodThis is an

resultsA significant reduction in SOD activity (p=0.022) was found between the NC and PC groups but not in MDA level (p=0.394). SOD activity increased significantly in T2 when compared to PC (p=0.007). MDA levels significantly increased at T1 (p=0.002), T2 (p=0.005), and T3 (p=0.006) when compared to PC.

conclusionBlack cumin ethanolic extract increased SOD activity in Wistar rats exposed to cigarette smoke. However, no reduce of MDA level was observed.

Indexed as

Black CuminCigarette SmokeEndothelial DysfunctionMalondialdehydeSuperoxide Dismutase

Identifiers

PMID40231021
PMCPMC11994053

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.