ArticleBioinformation2024
Analysis of protein interaction network in obesity linked with periodontitis.
Article in Bioinformation, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- From the Proteome to Therapeutics: A Multi-Database Approach to Drug Discovery in Periodontitis-An Exploratory Pilot Study.Journal of clinical periodontology · 2026Article
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The clinical link between obesity and periodontitis by investigating the potential interaction among proteins is of interest. A protein-protein interaction (PPI) network analysis using STRING was conducted on novel proteins identified from saliva samples through quantitative proteomics and mass spectrometry. Twenty proteins were involved in molecular process, cellular components and biological functions focusing on proteins with variants closely associated with obesity and periodontitis. Analysis revealed that PPI network exhibited a high degree of interactions, indicating a biological connection with a significant p value 4.8*105. These PPIs discuss the interplay between obesity and periodontitis, require further experimental validation, unravel new clues for downstream studies and propose biological mechanisms through which these two conditions may interact.
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