ArticleFrontiers in pediatrics2025
Comparative analysis of adenovirus and rotavirus gastroenteritis: insights into inflammatory response and temporal variations.
Article in Frontiers in pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Abstract
Background: Acute viral gastroenteritis remains a leading cause of healthcare costs globally, prompting the need for effective yet simple diagnostic strategies. This study aimed to comprehensively examine the demographic, clinical, and seasonal characteristics, hemogram parameters, and C-reactive protein levels in children diagnosed with adenovirus and rotavirus gastroenteritis. Methods: By conducting a retrospective study, three groups of children diagnosed with gastroenteritis (Rotavirus positive, adenovirus positive, and rota/adenovirus negative group) were compared in terms of demographic, clinical, and laboratory parameters. Results: Among 265 children with gastroenteritis, 59.6% were under 36 months, and 36.8% of this group tested positive for rotavirus, while 30% of them tested positive for adenovirus. A statistically significant association was observed between rotavirus gastroenteritis and high neutrophil/lymphocyte value (2.76 ± 1.52) and decreased mean platelet volume (7.47 ± 0.36 fL). Temporal analysis revealed numerical peaks in the adenovirus group in summer and rotavirus in winter; however, these differences were not statistically significant ( Conclusions: Our findings suggested that decreased mean platelet volume and high neutrophil/lymphocyte ratio were found statistically significant in rotavirus gastroenteritis, distinguishing it from other causes of acute gastroenteritis.
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