Evidence map›Paper›PMID 40230786›Full record

ArticleFrontiers in allergy2025

Fire ant-venom anaphylaxis prevalence in the general population and patients with systemic mastocytosis.

Jeremy C McMurray, Brandon J Schornack, Karla E Adams, Robert L McCoy, Amanda K Marshall, Janet A Brunader, Irina Maric, Dean D Metcalfe, Nathan A Boggs

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in allergy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jeremy C McMurrayAllergy & Immunology Service, Walter Reed National Military Medical Center, Bethesda, MD, United States.
Brandon J SchornackAllergy & Immunology Service, Walter Reed National Military Medical Center, Bethesda, MD, United States.
Karla E AdamsAllergy & Immunology Service, Wilford Hall Ambulatory Surgical Center, San Antonio, TX, United States.
Robert L McCoyThe United States Army Centralized Allergen Extract Laboratory (USACAEL), Silver Spring, MD, United States.
Amanda K MarshallDefense Health Agency, Defense Healthcare Management Systems, Falls Church, VA, United States.
Janet A BrunaderDefense Health Agency Immunization Healthcare Division, Falls Church, VA, United States.
Irina MaricHematology Section, Department of Laboratory Medicine, National Institutes of Health, Bethesda, MD, United States.
Dean D MetcalfeLaboratory of Allergic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, United States.
Nathan A BoggsAllergy & Immunology Service, Walter Reed National Military Medical Center, Bethesda, MD, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Stinging Hymenoptera can induce fatal anaphylaxis, especially in patients with systemic mastocytosis. Fire ants, Methods: We queried the beneficiary immunotherapy prescription database for patients who received immunotherapy with Hymenoptera venom or fire ant whole-body extract and the Tricare beneficiary population health registry database for patients with an ICD-10 code for Hymenoptera venom allergy (HVA). Greater than 95% of the beneficiary population were patients living in the United States. Chart review of a random sample of 150 patients linked to a HVA ICD-10 code was performed to determine the percent of patients with Hymenoptera-venom anaphylaxis. Retrospective review of a systemic mastocytosis cohort was performed to assess fire ant-venom anaphylaxis rate and treatment patterns. Results: Fire ant immunotherapy was the most frequently ordered individual immunotherapy prescription 45.9% ( Conclusion: Fire ant-venom anaphylaxis prevalence in the general population and patients with systemic mastocytosis is higher than all flying Hymenoptera-venom anaphylaxis combined in colonized states. Fire ant-venom anaphylaxis in systemic mastocytosis is frequently misdiagnosed and not treated with epinephrine.

Indexed as

fire ant-venom anaphylaxis prevalenceflying hymenoptera-venom anaphylaxis prevalencered and black fire antsSolenopsis invicta and richterisystemic mastocytosis (SM)

Identifiers

PMID40230786
PMCPMC11994729

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.