Evidence map›Paper›PMID 40230773›Full record

ArticleCureus2025

Non-invasive Hyperglycemia Detection via Electrocardiogram Using Discrete Wavelet Transform and Machine Learning.

Oscar I Coronado-Reyes, Adriana C Téllez-Anguiano, Luis A Castro-Pimentel, Jose A Gutierrez-Gnecchi

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In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Oscar I Coronado-ReyesGraduate Studies and Research Division, TecNM Instituto Tecnológico de Morelia, Morelia, MEX.
Adriana C Téllez-AnguianoGraduate Studies and Research Division, TecNM Instituto Tecnológico de Morelia, Morelia, MEX.
Luis A Castro-PimentelGraduate Studies and Research Division, TecNM Instituto Tecnológico de Morelia, Morelia, MEX.
Jose A Gutierrez-GnecchiGraduate Studies and Research Division, TecNM Instituto Tecnológico de Morelia, Morelia, MEX.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

INTRODUCTION AND

aimDiabetes mellitus (DM) is a chronic metabolic disorder characterized by elevated blood glucose levels (BGLs), traditionally monitored through invasive methods. Continuous monitoring of BGL is essential to prevent severe complications. This study proposes a non-invasive approach to detect hyperglycemia by analyzing electrocardiogram (ECG) signals using the discrete wavelet transform (DWT) and machine learning techniques. The relationship between diabetes and electrocardiographic (ECG) signals is highly relevant in biomedicine, as DM is a significant risk factor for cardiovascular diseases. MATERIALS AND

methodsA total of 210 individuals (healthy and diabetic, aged 18-70 years) were analyzed, with ECG signals processed using DWT to extract heart rate (HR) in beats per minute (bpm) and heart rate variability (HRV) parameters. These features were used as inputs for support vector machine (SVM) and k-nearest neighbors (KNN) classifiers to distinguish between normal and hyperglycemic states (>150 mg/dL).

resultsThe DWT-based automatic feature detection achieved an accuracy of 99.8% for both HR and HRV. Pearson correlation analysis revealed moderate correlations between glucose levels and HR (0.2985) and HRV (-0.373), with a combined correlation index of 0.6428.

conclusionClassification results showed an accuracy of 97% for normal glucose levels and 93% for hyperglycemia detection using both SVM and KNN. These findings indicate that ECG signal characteristics can serve as an adjunct for non-invasive hyperglycemia detection.

Indexed as

diabetes mellitusdiscrete wavelet transformheart rate variabilityk-nearest neighborssupport vector machine

Identifiers

PMID40230773
PMCPMC11994367

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.