ReviewCureus2025
Advances in Neurological Pain Management: Bridging Scientific Innovations and Clinical Practice.
Review in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Neuronal pain, including neuropathic pain, migraines, and chronic pain syndromes, presents a significant global health challenge. This literature review covers studies conducted until 2024 using major databases, including PubMed and Google Scholar, with the search terms "Neuropathic Pain/therapy" OR "Chronic Pain/therapy" OR "Pain Management/methods" OR "Neuromodulation/methods" OR "Spinal Cord Stimulation" OR "Deep Brain Stimulation" OR "Transcranial Magnetic Stimulation" OR "Transcranial Direct Current Stimulation" OR "Nav1.7 Voltage-Gated Sodium Channel" OR "Biologics/pharmacology" OR "Drug Delivery Systems/methods" OR "Regenerative Medicine/methods" OR "Stem Cell Transplantation/methods" OR "Platelet-Rich Plasma/therapeutic use" OR "Tissue Engineering/methods" OR "Biomarkers/metabolism" OR "Machine Learning" OR "Precision Medicine." This review explores contemporary advancements in neurological pain therapy, emphasizing analytical studies that translate into clinical applications. The research foundation is built on modern literature examining pain mechanisms, pharmaceutical innovations, neuromodulation strategies, personalized pain management, and regenerative medicine. Notable advancements include neuroinflammation research, molecular and genetic pain factor discoveries, and the development of selective Nav1.7 inhibitors, biologics, and advanced drug delivery systems. Neuromodulation techniques, both invasive (e.g., deep brain stimulation (DBS), spinal cord stimulation (SCS)) and noninvasive (e.g., transcranial direct current stimulation (tDCS), transcranial magnetic stimulation (TMS)), play a crucial role in pain modulation. Regenerative approaches, including stem cell therapy, platelet-rich plasma (PRP), and tissue engineering, offer promising solutions for tissue repair and symptom relief. Additionally, genomic data, biomarkers, and machine learning enhance precision in pain management. Ethical considerations regarding treatment accessibility and opioid alternatives remain critical, particularly for Hispanic Americans facing language barriers in programs like Optum. Selective serotonin reuptake inhibitors (SSRIs) continue to be widely used in mental health treatment. In conclusion, the convergence of translational research, innovative therapies, and personalized medicine marks a transformative era in neurological pain management, improving patient outcomes and quality of life.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.