ArticleCureus2025
Sensory Aphasia After Cerebral Venous Sinus Thrombosis: Quantitative Evaluation of the Recovery Process of Language Function Using Tractography.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Cerebral venous sinus thrombosis (CVST) is a rare condition with high mortality that requires careful imaging evaluation. While arterial spin labeling (ASL) proves valuable for CVST assessment and diffusion tensor imaging (DTI) effectively evaluates language function in stroke, no studies have combined these techniques to assess the progression of higher brain dysfunction in CVST. A 59-year-old man presented with severe sensory aphasia. Magnetic resonance venography (MRV) showed left sigmoid sinus disruption with decreased proximal signal intensity, while conventional MRI showed no ischemic findings. The patient underwent sequential imaging with ASL and DTI using a 1.5 Tesla MRI system (SIGNA Explorer 1.5T, GE Healthcare Japan, Tokyo, Japan). The sensory aphasia was resolved by day two, coinciding with improvement in MRV and normalization of ASL findings. DTI tractography, analyzed using XTRACT auto-segmentation, showed changes in fractional anisotropy (FA) values of language-related white matter tracts that paralleled symptom improvement. Recovery of Chinese character reading and writing corresponded with changes in FA values in the inferior fronto-occipital and inferior longitudinal bundles, reflecting the resolution of venous congestion. This case demonstrates the complementary value of ASL and DTI in monitoring recovery from CVST. While ASL showed increased cerebral blood flow during the acute phase, DTI provided objective measures of functional recovery through changes in FA values in language-related white matter tracts. This combined imaging approach offers a promising method to assess both perfusion changes and functional recovery in CVST with associated higher brain dysfunction.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.