ArticleVeterinary medicine international2025
Molecular Characterization and Genetic Diversity of Isolated Foot-and-Mouth Disease Viruses Circulating in Cattle in The Mekong Delta Provinces, Vietnam.
Article in Veterinary medicine international, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Foot-and-mouth disease (FMD) is a highly contagious viral disease of cloven-footed livestock caused by foot-and-mouth disease virus (FMDV). FMD has significant impacts on farmers and national economies. The evolution and mutation of FMDV have contributed to the emergence of new strains of FMDV. Sequences of VP1 from 11 FMDV isolates in the Mekong Delta Provinces were obtained by Sanger sequencing technology. The phylogenetic analysis of VP1 sequence elucidated that 8 FMDV isolates including O-VN-CTU-VL01 (PP897837), O-VN-CTU-VL02 (PP897838), O-VN-CTU-TV01 (PP897840), O-VN-CTU-TV02 (PP897841), O-VN-CTU-TV03 (PP897842), O-VN-CTU-TV04 (PP897844), O-VN-CTU-BT04 (PP897847), and O-VN-CTU-BT05 (PP897847) were clustered into Group 1. On the other hand, 3 FMDV isolates including O-VN-CTU-BT01 (PP897844), O-VN-CTU-BT02 (PP897844), and O-VN-CTU-BT03 (PP897844) were clustered into Group 2. In addition, the nucleotide and deduced amino acid sequences of VP1 in Group 1 were closely related to lineage Mya-98, topotype SEA, and Type O (89%-93% nucleotide identity and 91%-99% amino acid identity). The similarity of FMDV isolates in Group 2 was closely related to lineage Pan Asia, topotype ME-SA, Type O (91.13%-94.53% and 96%-99.44% nucleotide and amino acid similarities, respectively). Analysis of amino acid sequences of VP1 illustrated several substitution mutations detected at amino acid positions 133-158 (the main antigenic site) in lineages Mya-98 (O/SEA) and Pan Asia, (O/ME-SA). Notably, a substitution mutation at position M144V was detected in FMDVs O-VN-CTU-VL1 (PP897837) and FMDV O-VN-CTU-TV1 (PP897840). No recombinant events were detected at VP1 sequences. In brief, genetic analysis of VP1 nucleotide and amino acid sequences of isolated FMDVs contributed to detecting the mutation which was able to cause the emergence of new strains as well as to elucidate the evolution of FMDVs circulating in the Mekong Delta Provinces.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.