ArticleRSC advances2025
3D quantitative phase imaging
Article in RSC advances, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
5 authors.
Funding
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Abstract
Quantitative phase imaging (QPI) is a versatile, label-free technique for investigating the morphological and biophysical properties of biological cells. Here, we used 3D QPI to study the behavior of human red blood cells (RBCs) across a saline gradient from 1% to 0%. RBCs are osmotic-sensitive, and their phase profiles provide important measures of membrane integrity, shape transitions, and lumen hemolysis. Deducing phase alterations across each concentration allowed us to quantify the osmotic impacts on RBC morphology and assess the corresponding biophysical changes. Other studies on osmotic shock contributed to understanding the behavior of RBCs in hypotonic environments and their applications in hematological and biomedical fields.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.