Evidence map›Paper›PMID 40230622›Full record

ArticleMolecular therapy. Nucleic acids2025

Binding of G-quadruplex DNA and serum albumins by synthetic non-proteinogenic amino acids: Implications for c-Myc-related anticancer activity and drug delivery.

Hayarpi Simonyan, Rosanna Palumbo, Caterina Vicidomini, Pasqualina Liana Scognamiglio, Satenik Petrosyan, Lusine Sahakyan, Gagik Melikyan, Ashot Saghyan, Giovanni N Roviello

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular therapy. Nucleic acids, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
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  7. ARSC advances · 2025
    Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Hayarpi SimonyanInstitute of Pharmacy, Yerevan State University, 1 Alex Manoogian Str., Yerevan 0025, Armenia.
Rosanna PalumboInstitute of Biostructures and Bioimaging, Italian National Council for Research (IBB-CNR), Area di Ricerca Site and Headquarters, Via Pietro Castellino 111, 80131 Naples, Italy.
Caterina VicidominiInstitute of Biostructures and Bioimaging, Italian National Council for Research (IBB-CNR), Area di Ricerca Site and Headquarters, Via Pietro Castellino 111, 80131 Naples, Italy.
Pasqualina Liana ScognamiglioDepartment of Sciences, University of Basilicata, Via dell'Ateneo Lucano 10, 85100 Potenza, Italy.
Satenik PetrosyanInstitute of Pharmacy, Yerevan State University, 1 Alex Manoogian Str., Yerevan 0025, Armenia.
Lusine SahakyanInstitute of Pharmacy, Yerevan State University, 1 Alex Manoogian Str., Yerevan 0025, Armenia.
Gagik MelikyanInstitute of Pharmacy, Yerevan State University, 1 Alex Manoogian Str., Yerevan 0025, Armenia.
Ashot SaghyanInstitute of Pharmacy, Yerevan State University, 1 Alex Manoogian Str., Yerevan 0025, Armenia.
Giovanni N RovielloInstitute of Biostructures and Bioimaging, Italian National Council for Research (IBB-CNR), Area di Ricerca Site and Headquarters, Via Pietro Castellino 111, 80131 Naples, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study delves into the impact of two synthetic non-natural amino acids,

Indexed as

asymmetric synthesisc-MycfluorescenceG-quadruplexheterocyclic compoundsmolecular dockingMT: Oligonucleotides: Therapies and Applicationsnon-natural amino acidsoncogeneScanning Electron Microscopyspectroscopy

Identifiers

PMID40230622
PMCPMC11995079

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.