Evidence map›Paper›PMID 40230584›Full record

ArticleOne health (Amsterdam, Netherlands)2025

Serological evaluation of Crimean-Congo Hemorrhagic fever in humans with High-Risk professional exposure and in residual sera collected in 2022-2023 across Corsica (France).

Paloma Kiwan, Morena Gasparine, Dorine Decarreaux, Lisandru Capai, Shirley Masse, Miša Korva, Tatjana Avšič-Županc, Jean Canarelli, Marie-Helene Simeoni, Xavier de Lamballerie and 2 more

Abstract read
In one paragraph

Article in One health (Amsterdam, Netherlands), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Paloma KiwanUnité des Virus Émergents (Aix Marseille Université, Università di Corsica, IRD 190, INSERM 1207, IRBA), Marseille, France.
Morena GasparineUnité des Virus Émergents (Aix Marseille Université, Università di Corsica, IRD 190, INSERM 1207, IRBA), Marseille, France.
Dorine DecarreauxUnité des Virus Émergents (Aix Marseille Université, Università di Corsica, IRD 190, INSERM 1207, IRBA), Marseille, France.
Lisandru CapaiUnité des Virus Émergents (Aix Marseille Université, Università di Corsica, IRD 190, INSERM 1207, IRBA), Marseille, France.
Shirley MasseUnité des Virus Émergents (Aix Marseille Université, Università di Corsica, IRD 190, INSERM 1207, IRBA), Marseille, France.
Miša KorvaInstitute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia.
Tatjana Avšič-ŽupancInstitute of Microbiology and Immunology, Faculty of Medicine, University of Ljubljana, Ljubljana, Slovenia.
Jean CanarelliLaboratoire de Biologie Médicale CCF, Ajaccio, France.
Marie-Helene SimeoniLaboratoire de Biologie Médicale 2A2B, Corte, France.
Xavier de LamballerieUnité des Virus Émergents (Aix Marseille Université, Università di Corsica, IRD 190, INSERM 1207, IRBA), Marseille, France.
Remi CharrelUnité des Virus Émergents (Aix Marseille Université, Università di Corsica, IRD 190, INSERM 1207, IRBA), Marseille, France.
Alessandra FalchiUnité des Virus Émergents (Aix Marseille Université, Università di Corsica, IRD 190, INSERM 1207, IRBA), Marseille, France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The Crimean-Congo hemorrhagic fever virus (CCHFV) is a tick-borne pathogen known to cause severe viral hemorrhagic fever. Aim: We aimed to evaluate the potential circulation of CCHFV in Corsica through a serosurvey, including anonymized residual sera (RS) and high-risk individuals exposed to animals and/or tick bites due to occupational activities. Methods: This cross-sectional study involved two groups: anonymized RS from medical biology laboratories and sera from high-risk individuals (slaughterhouse workers, veterinary professionals, animal farmers, and rangers) collected across Corsica during 2022-2023. Antibodies targeting the CCHFV viral nucleoprotein were detected using a double-antigen ELISA. ELISA-positive samples underwent neutralizing antibody testing. Sociodemographic and epidemiological data were collected using a structured questionnaire in the high-risk group. Results: Total anti-CCHFV seropositivity was of 0.08 % ( Conclusions: This study provides initial evidence of human exposure to CCHFV in Corsica, with rates consistent with those observed in other Western European regions. Our results indicate a risk of CCHF among the Corsican population, particularly among farmers and slaughterhouse workers. Continuous surveillance and public education are essential to mitigate this risk, especially among these targeted groups and healthcare professionals, ensuring prompt diagnosis and prevention of potential outbreaks.

Indexed as

CorsicaCrimean-Congo Hemorrhagic Fever Virus (CCHFV)High-riskHuman populationsSeroprevalenceTick biteTick-borne virus

Identifiers

PMID40230584
PMCPMC11995033

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.