Evidence map›Paper›PMID 40230520›Full record

ArticleiScience2025

Gut microbiome remodeling provides protection from an environmental toxin.

Dan Kim, Sarah El Khoury, Olga Maria Pérez-Carrascal, Catherin DeSousa, Da Kyung Jung, Seneca Bohley, Lila Wijaya, Kenneth Trang, Michael Shapira

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in iScience, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Environmental science. Processes & impacts · 2026
    Article
  2. Article
  3. Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Dan KimDepartment of Integrative Biology, University of California, Berkeley, Berkeley, CA 94720, USA.
Sarah El KhouryDepartment of Integrative Biology, University of California, Berkeley, Berkeley, CA 94720, USA.
Olga Maria Pérez-CarrascalDepartment of Integrative Biology, University of California, Berkeley, Berkeley, CA 94720, USA.
Catherin DeSousaDepartment of Integrative Biology, University of California, Berkeley, Berkeley, CA 94720, USA.
Da Kyung JungDepartment of Integrative Biology, University of California, Berkeley, Berkeley, CA 94720, USA.
Seneca BohleyDepartment of Integrative Biology, University of California, Berkeley, Berkeley, CA 94720, USA.
Lila WijayaDepartment of Integrative Biology, University of California, Berkeley, Berkeley, CA 94720, USA.
Kenneth TrangDepartment of Integrative Biology, University of California, Berkeley, Berkeley, CA 94720, USA.
Michael ShapiraDepartment of Integrative Biology, University of California, Berkeley, Berkeley, CA 94720, USA.

Funding

The role of the gut microbiome in host adaptation to environmental xenobiotics - mechanisms and long-term consequencesR01ES034012 · NIEHS · UNIVERSITY OF CALIFORNIA BERKELEY · PI Michael Shapira · 2022 to 2026
$1.8M
Training Program in Metabolic BiologyT32DK128783 · NIDDK · UNIVERSITY OF CALIFORNIA BERKELEY · PI Andreas Stahl · 2022 to 2026
$776k
NIDDK NIH HHS T32 DK128783NIEHS NIH HHS R01 ES034012
6 · The paper itself

Abstract

Gut microbiomes contribute to animal health and fitness. The immense biochemical diversity of bacteria holds particular potential for neutralizing environmental toxins and thus helping hosts deal with new toxic challenges. To explore this potential, we used

Indexed as

MicrobiologyMicrobiome

Identifiers

PMID40230520
PMCPMC11995125

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.