Evidence map›Paper›PMID 40230518›Full record

ReviewThe Lancet regional health. Western Pacific2025

Is Southeast Asia and the Western Pacific ready for potential monkeypox virus outbreaks?

Janhavi A, Gregory Gan, Akira Endo, Rayner Kay Jin Tan, Kiesha Prem, Borame Lee Dickens

Abstract readReview
In one paragraph

Review in The Lancet regional health. Western Pacific, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Mpox and the one health approach.Dialogues in health · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Janhavi ASaw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore, Singapore.
Gregory GanSaw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore, Singapore.
Akira EndoSaw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore, Singapore.
Rayner Kay Jin TanSaw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore, Singapore.
Kiesha PremSaw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore, Singapore.
Borame Lee DickensSaw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore, Singapore.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The new variant of the monkeypox virus (MPXV) clade Ib has recently spread to other African countries outside the Democratic Republic of the Congo (DRC), prompting the World Health Organisation to declare the outbreak as a public health emergency of international concern (PHEIC). This comes just two years after the initial PHEIC that was issued for the clade IIb outbreaks. Compared to the clade IIb outbreaks, clade Ib shows a demographic shift, including higher case fatality rates for younger individuals, indicating a possibility of additional transmission pathways through heterosexual and household contacts. Given that many countries in the Western Pacific (WPR) and the Southeast Asian region (SEAR) hold a disproportionate burden of endemic infectious diseases and have difficulties engaging key at-risk populations, an outbreak of the potentially more virulent clade Ib virus could have devastating impacts on the health care systems. Thus, strategy planning against the potential emergence of clade Ib MPXV in the regions is required, including surveillance systems for detection, modelling studies to perform risk assessments, implementation of non-pharmaceutical interventions, and vaccination, and regional collaboration to ensure equitable distribution of vaccinations.

Indexed as

Emerging infectious diseasempoxOutbreak readiness

Identifiers

PMID40230518
PMCPMC11994344

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.