Evidence map›Paper›PMID 40230500›Full record

ReviewInternational journal of cardiology. Heart & vasculature2025

Periprocedural care for frail older patients with aortic stenosis undergoing transcatheter aortic valve replacement.

Joshua Eng, Jie Jun Wong, Kay Woon Ho, Angela S Koh, Ru-San Tan

Abstract readReview
In one paragraph

Review in International journal of cardiology. Heart & vasculature, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trends and Projections for Aortic Stenosis and Hypertension-Related Mortality Among Older Adults in the United States: A Retrospective Population-Based Analysis.High blood pressure & cardiovascular prevention : the official journal of the Italian Society of Hypertension · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Joshua EngDepartment of Cardiology, National Heart Centre Singapore, 5 Hospital Drive, 169609, Singapore.
Jie Jun WongDepartment of Cardiology, National Heart Centre Singapore, 5 Hospital Drive, 169609, Singapore.
Kay Woon HoDepartment of Cardiology, National Heart Centre Singapore, 5 Hospital Drive, 169609, Singapore.
Angela S KohDepartment of Cardiology, National Heart Centre Singapore, 5 Hospital Drive, 169609, Singapore.
Ru-San TanDepartment of Cardiology, National Heart Centre Singapore, 5 Hospital Drive, 169609, Singapore.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Degenerative aortic stenosis (AS) is an aging-associated disease with alarmingly high mortality that has risen in prevalence in tandem with the global population aging. Treatment options for AS are currently limited to surgical or percutaneous valve intervention, which are associated with significant morbidity. It is increasingly recognized that the care of AS patients is frequently constrained by concomitant frailty, an under-recognized syndrome among older individuals. Many AS patients have concurrent aging-associated diseases, including atherosclerotic diseases, organ impairment, physical frailty, and nutritional deficiencies which limit functional improvement after valve intervention. It has become increasingly crucial for clinicians to address these concurrent issues in frail, older individuals with AS to achieve the best possible outcomes. We aim to review the well-studied relationship between frailty and AS, as well as possible strategies for periprocedural optimization and risk management.

Indexed as

FrailtyPerioperative careTranscatheter aortic valve replacement

Identifiers

PMID40230500
PMCPMC11995748

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.