Evidence map›Paper›PMID 40230464›Full record

ArticleFrontiers in bioengineering and biotechnology2025

Analysis of the intrinsic value of life in the context of synthetic biology.

Yi Zhang, Yuling Chen, Bohua Liao

Abstract read
In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Yi ZhangOffice of Academic Research, Fujian Institute of Socialism, Fuzhou, China.
Yuling ChenSchool of Marxism, Ningbo University of Finance and Economics, Ningbo, China.
Bohua LiaoCollege of Rural Revitalization, Fujian Agriculture and Forestry University, Fuzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The ongoing advancements in synthetic biology, employing either "bottom-up" or "top-down" approaches to construct synthetic life, are generating significant interest. However, the broad application of these scientific practices remains fraught with ethical controversies. Thus, investigating the intrinsic value associated with synthetic life is crucial for determining whether and how synthetic life should be constructed and utilized. This study draws upon and extends Ronald Sandler's theory of intrinsic value, analyzing the intrinsic subjective value of synthetic life from the perspectives of ecocentrism, human culture, and the structural properties of synthetic life itself. It examines the intrinsic objective value of synthetic life based on its natural purposes. Additionally, the study explores the inherent worth of synthetic life from three angles: biology, subjectivity, and relationships with human beings. We conclude that the intrinsic value of synthetic life increases sequentially from synthetic microorganisms to synthetic plants, synthetic invertebrates, synthetic vertebrates, and synthetic humans. All forms of synthetic life possess intrinsic subjective and objective value. However, only synthetic life above the grade of synthetic microorganisms has inherent worth; thus, humans have moral obligations towards them.

Indexed as

intrinsic valuemoral statussynthetic biologysynthetic lifevalue

Identifiers

PMID40230464
PMCPMC11994678

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.