Evidence map›Paper›PMID 40230425›Full record

ArticleOncology letters2025

Myoepithelial carcinoma of submaxillary gland: A case report.

Yuetian Li, Quanyi Wang

Abstract readCase Reports
In one paragraph

Article in Oncology letters, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Yuetian LiClinical School of Medicine, Jining Medical University, Jining, Shandong 272067, P.R. China.
Quanyi WangDepartment of Pathology, Affiliated Hospital of Jining Medical University, Jining, Shandong 272029, P.R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Myoepithelial carcinoma (MEC) is a malignant tumour composed almost entirely of cells differentiated from the myoepithelium. It is rare, most commonly occurring in the parotid gland. In the current study, a rare case of MEC in the submandibular gland was presented. An 82-year-old male patient was admitted with a swelling in the upper left neck that had been present for 60 years. Magnetic resonance imaging indicated a tumour in the region of the left submandibular gland, which was not easy to clearly distinguish from the gland itself and an enhancement scan was recommended but not performed. Furthermore, multiple lymph nodes of varying sizes were present in the submandibular region of the neck on both sides. These enlarged lymph nodes had signs of involvement. Accordingly, a surgery was performed. The pathological diagnosis indicated the presence of a malignant tumour in the left upper neck. The tumour was most likely an MEC with pleomorphic adenoma, based on the results of immunohistochemistry. The size of the tumour mass was 5×5×4 cm. Histology indicated that the tumour cells exhibited infiltrative growth, with a sparse arrangement and a predominance of hyaline and spindle-shaped cells. In certain regions, the tumour tissue displayed characteristics similar to pleomorphic adenoma. The results of the immunohistochemical analysis were as follows: CD31(-), CD34(-), cytokeratin (CK)7 (+), vimentin (+), Ki-67 (+, 70%), erythroid growth factor receptor (-), desmin (-), anaplastic lymphoma kinase (-), P40 (+), CK pan-antibody (+) and epithelial membrane antigen (-). The patient underwent a surgical procedure to remove the lesion in the neck under sedation with complex anaesthesia. The sample excised from the surgery was sent to the pathology department for diagnosis. Given the high recurrence frequency of MEC, monitoring patients closely after surgery is crucial.

Indexed as

clinicopathological featuresimmunohistochemistrymyoepithelial carcinomapleomorphic adenomasubmandibular gland

Identifiers

PMID40230425
PMCPMC11995683

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.