Evidence map›Paper›PMID 40230324›Full record

Observational studyColorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland2025

AUGUR-AIM: Clinical validation of an artificial intelligence indocyanine green fluorescence angiography expert representer.

Philip D Mc Entee, Patrick A Boland, Ronan A Cahill

Abstract readValidation StudyObservational StudyMulticenter Study
In one paragraph

Observational study in Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. AUGUR-AIM: Clinical validation of an artificial intelligence indocyanine green fluorescence angiography expert representer.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2025
    Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Philip D Mc EnteeUCD Centre for Precision Surgery, UCD, Dublin, Ireland.ORCID 0000-0002-3907-5398
Patrick A BolandUCD Centre for Precision Surgery, UCD, Dublin, Ireland.
Ronan A CahillUCD Centre for Precision Surgery, UCD, Dublin, Ireland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimRecent randomized controlled trials and meta-analyses have demonstrated a reduction in the anastomotic leak rate when indocyanine green fluorescence angiography (ICGFA) is used versus when it is not in colorectal resections. We have previously demonstrated that an artificial intelligence (AI) model, AUGUR-AI, can digitally represent in real time where experienced ICGFA users would place their surgical stapler based on their interpretation of the fluorescence imagery. The aim of this study, called AUGUR-AIM, is to validate this method across multiple clinical sites with regard to generalizability, usability and accuracy while generating new algorithms for testing and determining the optimal mode of deployment for the software device.

methodThis is a prospective, observational, multicentre European study involving patients undergoing resectional colorectal surgery with ICGFA as part of their standard clinical care enrolled over a 1-year period. Video recordings of the ICGFA imagery will be computationally analysed both in real time and post hoc by AUGUR-AI, with the operating surgeon blinded to the results, testing developed algorithms iteratively versus the actual surgeon's ICGFA interpretation. AI-based interpretation of the fluorescence signal will be compared with the actual transection site selected by the operating surgeon and usability optimized.

conclusionAUGUR-AIM will validate the use of AUGUR-AI to interpret ICGFA imagery in real time to the level of an expert ICGFA user, building on our previous work to include a larger, more diverse patient and surgeon population. This could allow future progression to develop the AI model into a usable clinical tool that could provide decision support, including to new/infrequent ICGFA users, and documentary support of the decision made by experienced users.

Indexed as

Anastomotic LeakArtificial IntelligenceFluorescein AngiographyIndocyanine GreenAlgorithmsColoring AgentsEuropeHumansMulticenter Studies as TopicProspective StudiesColoring AgentsIndocyanine Greenartificial intelligencecolorectal surgeryexpert interpretationfluorescence angiographyindocyanine green

Identifiers

PMID40230324
PMCPMC11997639

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.