ArticlePediatric pulmonology2025
Effects of Obesity and Sex on Supine Functional Residual Capacity and Expiratory Flow Limitation in Children.
Article in Pediatric pulmonology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
introductionChildhood obesity is associated with a higher risk of sleep-disordered breathing, but our understanding of the underlying physiologic mechanisms is limited. This study investigated the effects of obesity on lung volumes, expiratory flow limitation (EFL), and respiratory symptoms in the supine position.
methodsNinety-four children (8-12 years old, n = 58 with obesity and n = 36 without obesity) underwent lung volume and EFL measurements in the seated and supine positions in this repeated-measures cross-sectional study. Children without obesity underwent an additional condition where either a 2.3 kg (n = 26) or 5.0 kg (n = 8) mass was placed on their abdomen to simulate obesity. Ratings of perceived breathlessness (RPB) were recorded.
resultsFunctional residual capacity (FRC) in the supine when compared with the seated posture decreased more so in children without obesity (43.9 ± 1.0 vs. 34.4 ± 1.0% total lung capacity [TLC]) compared with children with obesity (35.5 ± 0.8 vs. 29.6 ± 0.8% TLC; p = 0.0048 group*posture). EFL in the supine position was present in 17% of children with obesity compared with 6% of children without obesity (p = 0.1218). In children without obesity, mass-loading with 5.0 kg produced further reductions in FRC (seated: 45.0 ± 1.7% TLC; supine: 36.7 ± 1.7% TLC; supine+5.0 kg: 29.4 ± 1.7% TLC; p = 0.0087 seated vs. supine+ and p = 0.0178 supine vs. supine + ) and an increase in RPB (seated: 0.38 ± 0.24; supine: 0.42 ± 0.24; supine+5.0 kg: 1.25 ± 0.27; p = 0.0002 seated vs. supine+ and p = 0.0001 supine vs. supine + ).
conclusionsChildren with obesity breathe at significantly lower lung volumes while supine, increasing the risk of EFL. A better physiologic understanding of the mechanical effects of obesity could potentially improve the management of sleep-related symptoms among children with obesity.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.