Evidence map›Paper›PMID 40229975›Full record

ArticleEarly intervention in psychiatry2025

Brief Report: Intact Cognitive Functions in Children and Adolescents of Parents With Mood Disorders.

Mélanie Boisvert, Jules R Dugré, Stéphane Potvin

Abstract read
In one paragraph

Article in Early intervention in psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Mélanie BoisvertResearch Center of the Institut Universitaire en Santé Mentale de Montréal, Montreal, Canada.
Jules R DugréSchool of Psychology and Centre for Human Brain Health, University of Birmingham, Birmingham, UK.
Stéphane PotvinResearch Center of the Institut Universitaire en Santé Mentale de Montréal, Montreal, Canada.ORCID https://orcid.org/0000-0003-1624-378X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesWe aimed to identify if offspring of a parent with mood disorders presented cognitive deficits on 14 cognitive subtests while controlling for intellectual quotient, anxio-depressive symptoms, symptoms of attention deficit hyperactivity disorder (ADHD) or insomnia.

methodsUsing the Healthy Brain Network biobank, we identified 44 offspring of a parent with bipolar disorder (BD), 87 offspring of a parent with major depressive disorder (MDD) and 88 offspring of healthy parents. Analyses of variance (ANOVA) were performed to determine if groups differed on 14 subtests of the Wechsler Intelligence Scale for Children-5th Edition (WISC) and National Institutes of Health toolbox.

resultsAcross all subtests, groups did not significantly differ. Only a subtle effect was found for male participants in which high-risk participants exhibited lower scores on the mental rotation subtest compared to the control group.

conclusionOverall, our results suggest intact cognition in young offspring of parents with a mood disorder.

Indexed as

Bipolar DisorderChild of Impaired ParentsCognitionMajor Depressive DisorderMood DisordersAdolescentAdultChildFemaleHumansMaleNeuropsychological TestsParentsbipolar disordercognitionmajor depressive disorderWISC

Identifiers

PMID40229975
PMCPMC11997297

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.