Evidence map›Paper›PMID 40229974›Full record

ArticleAdvanced science (Weinheim, Baden-Wurttemberg, Germany)2025

Low-Irradiance Antimicrobial Blue Light-Bathing Therapy for Wound Infection Control.

Jie Hui, Wonjoon Moon, Pu-Ting Dong, Carolina Dos Anjos, Laisa Negri, Hao Yan, Ying Wang, Joshua Tam, Tianhong Dai, R Rox Anderson and 3 more

Abstract read
In one paragraph

Article in Advanced science (Weinheim, Baden-Wurttemberg, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Low-Irradiance Antimicrobial Blue Light-Bathing Therapy for Wound Infection Control.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Jie HuiWellman Center for Photomedicine, Massachusetts General Hospital, Boston, MA, 02139, USA.
Wonjoon MoonWellman Center for Photomedicine, Massachusetts General Hospital, Boston, MA, 02139, USA.
Pu-Ting DongDepartment of Microbiology, The ADA Forsyth Institute, Boston, MA, 02142, USA.
Carolina Dos AnjosWellman Center for Photomedicine, Massachusetts General Hospital, Boston, MA, 02139, USA.
Laisa NegriWellman Center for Photomedicine, Massachusetts General Hospital, Boston, MA, 02139, USA.
Hao YanWellman Center for Photomedicine, Massachusetts General Hospital, Boston, MA, 02139, USA.
Ying WangWellman Center for Photomedicine, Massachusetts General Hospital, Boston, MA, 02139, USA.
Joshua TamWellman Center for Photomedicine, Massachusetts General Hospital, Boston, MA, 02139, USA.
Tianhong DaiWellman Center for Photomedicine, Massachusetts General Hospital, Boston, MA, 02139, USA.
R Rox AndersonWellman Center for Photomedicine, Massachusetts General Hospital, Boston, MA, 02139, USA.
Jeremy GovermanDepartment of Surgery, Harvard Medical School, Boston, MA, 02115, USA.
Jeffrey A GelfandWellman Center for Photomedicine, Massachusetts General Hospital, Boston, MA, 02139, USA.
Seok-Hyun YunWellman Center for Photomedicine, Massachusetts General Hospital, Boston, MA, 02139, USA.ORCID https://orcid.org/0000-0002-8176-9916

Funding

Air Force Office of Scientific Research Military Medical Photonics Program FA9550-20-1-0063
6 · The paper itself

Abstract

The prevalence of antibiotic resistance and tolerance in wound infection management poses a serious and growing health threat, necessitating the exploration of alternative approaches. Antimicrobial blue light therapy offers an appealing, non-pharmacological solution. However, its practical application has been hindered by the requirement for high irradiance levels (50-200 mW/cm

Indexed as

BathsPhototherapyWound InfectionAnimalsBlue LightDisease Models, AnimalMaleMethicillin-Resistant Staphylococcus aureusPseudomonas aeruginosaPseudomonas InfectionsRatsRats, Sprague-DawleyStaphylococcal InfectionsWound Healingantimicrobial blue lightantimicrobial resistancemedical devicephototherapywound infection

Identifiers

PMID40229974
PMCPMC12120825

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.