Evidence map›Paper›PMID 40229889›Full record

SynthesisEuropean journal of medical research2025

Comparison of video laryngoscopy with direct laryngoscopy in critically ill patients: a systematic review and meta-analysis of randomized controlled trials.

Jun Yuan, Penglei Yang, Lina Yu, Wenguang Zhang, Jiangquan Yu, Qihong Chen

Abstract readSystematic ReviewMeta-AnalysisComparative Study
In one paragraph

Synthesis in European journal of medical research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jun Yuan *Department of Critical Care Medicine, Jiangdu People's Hospital Affiliated to Yangzhou University, Yangzhou, 225200, China.
Penglei Yang *Department of Critical Care Medicine, Jiangdu People's Hospital Affiliated to Yangzhou University, Yangzhou, 225200, China.
Lina YuDepartment of Critical Care Medicine, Jiangdu People's Hospital Affiliated to Yangzhou University, Yangzhou, 225200, China.
Wenguang ZhangDepartment of Emergency, Jingjiang People's Hospital, Jingjiang, 214599, China.
Jiangquan YuDepartment of Critical Care Medicine, Northern Jiangsu People's Hospital, Yangzhou, 225001, Jiangsu, China.
Qihong ChenDepartment of Critical Care Medicine, Jiangdu People's Hospital Affiliated to Yangzhou University, Yangzhou, 225200, China. jiangdurenyiicu@163.com.

Funding

Jiangsu Health Committee scientific research project Z2022008Yangzhou Health Commission 2023-2-27
6 · The paper itself

Abstract

backgroundAlthough Video laryngoscope (VL) can reduce the difficulty of endotracheal intubation and improve the glottic view, its use in critically ill patients is controversial.

methodsRandomized controlled trials (RCTs) of VL and direct laryngoscopy (DL) for critically ill patients were searched on electronic databases, including Web of Science, PubMed, and Embase. Additional publications were identified by screening the reference lists of the identified articles and relevant previously published reviews.

resultsOverall, 25 RCTs involving 5836 critically ill patients were included in the analysis. There was no significant difference in the first intubation rate between the VL and DL groups (25 studies; RR, 1.03; 95% CI 0.96-1.11; n = 5836; p = 0.37; very low certainty). However, Multivariate meta-regression analysis identified two main sources of bias: whether intubation was performed in a hospital (p = 0.04) and operator proficiency with DL compared to VL (p < 0.001). Subgroup analysis showed that VL improved the first intubation rate in in-hospital intubation (19 studies; RR, 1.12; 95% CI 1.04-1.22; n = 4441; p < 0.01, very low certainty) and VL showed good potential to reduce the first-attempt intubation success rates, but not significantly (6 studies; RR, 0.75; 95% CI 0.56-1.00; n = 1395; p = 0.05, very low certainty). In subgroups with similar operator proficiency VL and DL, VL increased the success rate for first intubation (16 studies; RR, 1.14; 95% CI 1.06-1.23; n = 3,971; p < 0.01; very low certainty). However, VL decreased the first intubation rate (4 studies; RR, 0.65; 95% CI 0.49-0.88; n = 810; p < 0.01; very low certainty) in a subgroup where operator proficiency was higher for DL than for VL.

conclusionVL does not increase the first intubation rate. However, VL increases the first-attempt intubation success rate for in-hospital intubation and operators with similar proficiency in VL and DL.

Indexed as

Critical IllnessIntubation, IntratrachealLaryngoscopyHumansRandomized Controlled Trials as TopicDirect laryngoscopyRandomized controlled trialsSystematic review and meta-analysisVideo laryngoscopy

Identifiers

PMID40229889
PMCPMC11998270

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.