ArticleBMC cancer2025
Nomogram model for predicting the long-term prognosis of cervical cancer patients: a population-based study in Mato Grosso, Brazil.
Article in BMC cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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3 citing papers in PubMed.
- Article
- Prognostic value of the lactate dehydrogenase-to-albumin ratio (LAR) combined with clinicopathological indicators for predicting outcomes in locally advanced cervical cancer undergoing concurrent chemoradiotherapy: a retrospective cohort study and nomogram development.American journal of cancer research · 2026Article
- Machine Learning-Based Prognostic Modelling Using MRI Radiomic Data in Cervical Cancer Treated with Definitive Chemoradiotherapy and Brachytherapy.Current oncology (Toronto, Ont.) · 2025Article
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6 authors.
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Abstract
backgroundCervical cancer (CC) is the third most common cancer among women worldwide and the second most prevalent neoplasm in Mato Grosso, Brazil, in 2020. This study aimed to analyze overall survival (OS), identify prognostic factors, and develop a nomogram to predict the long-term prognosis of CC patients using population-based data from Mato Grosso, Brazil.
methodsIntegrated data from the Mortality Information System (SIM) and the Population-Based Cancer Registry (RCBP) were used for patients diagnosed with CC between 2001 and 2018. Group differences were analyzed using the Log-rank test, and survival analysis was performed using the Kaplan-Meier method. Univariable and multivariable Cox regression models were applied to identify predictors of OS. A nomogram was developed to predict OS at 1, 3, 5, and 10 years. The accuracy of the model was assessed using the C-index, receiver operating characteristic (ROC) curve, and calibration plots.
resultsThe median follow-up time was 12 years (range: 6.28 - 17.1). The OS rates at 1, 3, 5, and 10 years were 95.4%, 91.3%, 89.9%, and 88.3%, respectively. Age, histological type, and disease stage were identified as independent prognostic factors for OS. The C-index for OS was 0.869, and the areas under the ROC curve for 1, 3, 5, and 10 years were 0.910, 0.897, 0.895, and 0.884, respectively, indicating good discrimination. The nomogram demonstrated good agreement with the observed survival rates.
conclusionThe developed nomogram predicts OS for CC patients at 1, 3, 5, and 10 years, showing good concordance with the observed survival rates and serving as a useful tool for guiding personalized interventions. Notably, disease staging and histopathological type were the most significant prognostic factors for OS.
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