Evidence map›Paper›PMID 40229694›Full record

ArticleBMC primary care2025

Diagnosing acute coronary syndrome in telephone triage: does it matter who initially calls? A cross-sectional study.

Mathé Delissen, Anique Sm Dobbe, Daphne Ca Erkelens, Loes Tc Wouters, Hester M den Ruijter, Joy Sa Corsel, Alja Sluiter, Frans H Rutten, Dorien Lm Zwart

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Article in BMC primary care, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

9 authors.

Mathé DelissenDeptartment General Practice & Nursing Science, Julius Centre for Health Sciences and Primary Care, University Medical Centre Utrecht, Utrecht University, Str.6.131, Heidelberglaan 100, PO Box 85500, Utrecht, 3508 GA, Netherlands. m.delissen-2@umcutrecht.nl.ORCID 0009-0002-7582-2343
Anique Sm DobbeDeptartment General Practice & Nursing Science, Julius Centre for Health Sciences and Primary Care, University Medical Centre Utrecht, Utrecht University, Str.6.131, Heidelberglaan 100, PO Box 85500, Utrecht, 3508 GA, Netherlands.
Daphne Ca ErkelensDeptartment General Practice & Nursing Science, Julius Centre for Health Sciences and Primary Care, University Medical Centre Utrecht, Utrecht University, Str.6.131, Heidelberglaan 100, PO Box 85500, Utrecht, 3508 GA, Netherlands.
Loes Tc WoutersDeptartment General Practice & Nursing Science, Julius Centre for Health Sciences and Primary Care, University Medical Centre Utrecht, Utrecht University, Str.6.131, Heidelberglaan 100, PO Box 85500, Utrecht, 3508 GA, Netherlands.
Hester M den RuijterLaboratory of Experimental Cardiology, University Medical Centre Utrecht, Utrecht University, Utrecht, Netherlands.
Joy Sa CorselDeptartment General Practice & Nursing Science, Julius Centre for Health Sciences and Primary Care, University Medical Centre Utrecht, Utrecht University, Str.6.131, Heidelberglaan 100, PO Box 85500, Utrecht, 3508 GA, Netherlands.
Alja SluiterNetherlands Triage Standard Foundation, Utrecht, Netherlands.
Frans H RuttenDeptartment General Practice & Nursing Science, Julius Centre for Health Sciences and Primary Care, University Medical Centre Utrecht, Utrecht University, Str.6.131, Heidelberglaan 100, PO Box 85500, Utrecht, 3508 GA, Netherlands.
Dorien Lm ZwartDeptartment General Practice & Nursing Science, Julius Centre for Health Sciences and Primary Care, University Medical Centre Utrecht, Utrecht University, Str.6.131, Heidelberglaan 100, PO Box 85500, Utrecht, 3508 GA, Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAdequate triage of patients with symptoms suggestive of ACS is crucial. Considering who calls might be useful to improve telephone triage of these patients. In this article, we aim to assess whether a call made by a surrogate is related to urgency allocation or higher odds of an acute coronary syndrome (ACS) than patient-initiated calls, and to assess possible gender differences.

methodsCross-sectional study of patients with symptoms suggestive of ACS who called the out-of-hours service in primary care (OHS-PC). Calls were classified into "patient-initiated call" or "surrogate call". Call and patient characteristics were collected. Odds ratios (OR) were calculated for the relationship between the type of call and (i) urgency allocation, (ii) ACS, and (iii) ACS or other life-threatening event, stratified for gender.

resultsIn total 2,428 recordings were included for analysis. Around half of the recordings were surrogate calls, and these more often received a high urgency (80.0%) than patient-initiated calls (57.8%), OR 2.92 (95%CI 2.44-3.50); in women OR 3.46, (95%CI 2.70-4.45), in men OR 2.42 (95%CI 1.86-3.16). Of all participants, 11.0% were diagnosed with an ACS; in women 8.0%, in men 14.7%. In the surrogate call group this was 14.4%, in the patient-initiated call group 7.6%; OR 2.04 (95%CI 1.57-2.67). In women, the OR was 2.46 (95%CI 1.63-3.77), in men 1.69 (95%CI 1.20-2.41).

conclusionsCompared to patients who call themselves, surrogate calls on behalf of a patient with symptoms suggestive of ACS receive more often a high urgency, and these patients have a risk twice as high of an ACS, an effect similar in women and men. It is useful for triage at the OHS-PC to consider who calls if it concerns a patient with symptoms suggestive of ACS. CLINICAL TRIAL NUMBER: NTR7331. Registration Date 26-06-2018.

Indexed as

Acute Coronary SyndromeAfter-Hours CareTelephoneTriageAgedCross-Sectional StudiesFemaleHumansMaleMiddle AgedPrimary Health CareSex FactorsAcute coronary syndromeGeneral practiceTelemedicineTriage

Identifiers

PMID40229694
PMCPMC11995617

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.