ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2025
Dynamics in distress and quality of life in patients undergoing radiation therapy: a prospective cohort study.
Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07698782 (Advanced Cancer Stage and Healthcare Coverage Predict Longitudinal Psychological Distress and Clinical Outcomes in Patients Undergoing Radiotherapy), which is not on this map. Cited by 7 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Advanced Cancer Stage and Healthcare Coverage Predict Longitudinal Psychological Distress and Clinical Outcomes in Patients Undergoing Radiotherapy
Who cites it
7 citing papers in PubMed.
- The Association Between Social Support and Psychosomatic Status in Cancer Patients During Mid-Course Radiotherapy: The Chain Mediating Roles of Psychological Capital and Coping Styles.Healthcare (Basel, Switzerland) · 2026Article
- Synergistic predictive value of T-stage and lymph node yield in guiding adjuvant radiotherapy decisions for pN1 OSCC without high-risk features: a multi-institutional retrospective cohort study.Clinical oral investigations · 2026Article
- Cost-Effectiveness of Radiotherapy and Its Impact on Patient Quality of Life: A Real-World Cost Utility Analysis in Greece.Current oncology (Toronto, Ont.) · 2026Article
- Article
- Review
- Redefining the therapeutic landscape of glioblastomas and brain metastasis through cesium brachytherapy and low-kV intra-operative radiation therapy (IORT).Journal of neuro-oncology · 2025Review
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThis study used a mobile-based assessment tool to evaluate the dynamics of distress and quality of life (QoL) in patients with esophageal, head and neck, and rectal cancers undergoing radiation therapy (RT).
methodsA prospective cohort study was conducted between November 2022 and July 2023 and included 100 patients who had completed assessments at pre-RT, weeks 2, 4, and 6 of RT, and 1 month post-treatment. The National Comprehensive Cancer Network Distress Thermometer and European Organization for Research and Treatment of Cancer Quality of Life Questionnaire were used.
resultsAll patients showed a 100% response rate to the mobile-based assessment at pre-RT, week 6, and post-treatment, with a 95% response rate at weeks 2 and 4 of RT. Of the 100 patients, 33% experienced marked distress pre-RT, with distress levels peaking at 67% at weeks 2 and 4. More than 50% of the patients reported experiencing sleep disturbance, fatigue, worry, or anxiety post-treatment. Their QoL dropped significantly during treatment from levels in weeks 2 and 4 and returned to pre-treatment levels post-RT. Higher distress was consistently correlated with poorer QoL. Emotional and physical issues such as pain and sleep disturbance were significantly associated with poor QoL pre- and post-RT.
conclusionRT was associated with increased distress and a temporary reduction in QoL. Key factors including sleep problems, fatigue, and emotional distress require targeted interventions to improve patient outcomes. Mobile technology use has proven effective in tracking distress and QoL in patients with cancer undergoing RT.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.