Evidence map›Paper›PMID 40229507›Full record

ArticleHistochemistry and cell biology2025

Analytical subcellular fractionation of microglial BV-2 cells with peroxisomal beta-oxidation defect.

Mounia Tahri-Joutey, Isabelle Hamer, Virginie Tevel, Quentin Raas, Catherine Gondcaille, Doriane Trompier, Riad El Kebbaj, Franck Ménétrier, Norbert Latruffe, Gérard Lizard and 5 more

Abstract read
PubMed Publisher
In one paragraph

Article in Histochemistry and cell biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. May In focus in HCB.Histochemistry and cell biology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Mounia Tahri-JouteyLaboratoire Biochimie, Faculté des Sciences et Techniques, Neurosciences, Ressources Naturelles et Environnement, Université Hassan I, BP577, 26000, Settat, Morocco.
Isabelle HamerPhysiological Chemistry Laboratory, URPhyM, NARILIS, University of Namur, Namur, Belgium.
Virginie TevelPhysiological Chemistry Laboratory, URPhyM, NARILIS, University of Namur, Namur, Belgium.
Quentin RaasCentre des Sciences du Goût et de l'Alimentation (CSGA), CNRS, INRAe, Institut Agro, Université de Bourgogne Europe, 21000, Dijon, France.
Catherine GondcailleCentre des Sciences du Goût et de l'Alimentation (CSGA), CNRS, INRAe, Institut Agro, Université de Bourgogne Europe, 21000, Dijon, France.
Doriane TrompierCentre des Sciences du Goût et de l'Alimentation (CSGA), CNRS, INRAe, Institut Agro, Université de Bourgogne Europe, 21000, Dijon, France.
Riad El KebbajSciences and Engineering of Biomedicals, Biophysics and Health Laboratory, Higher Institute of Health Sciences, Hassan First University, 26000, Settat, Morocco.
Franck MénétrierCentre des Sciences du Goût et de l'Alimentation (CSGA), CNRS, INRAe, Institut Agro, Université de Bourgogne Europe, 21000, Dijon, France.
Norbert LatruffeCentre des Sciences du Goût et de l'Alimentation (CSGA), CNRS, INRAe, Institut Agro, Université de Bourgogne Europe, 21000, Dijon, France.
Gérard LizardCentre des Sciences du Goût et de l'Alimentation (CSGA), CNRS, INRAe, Institut Agro, Université de Bourgogne Europe, 21000, Dijon, France.
Boubker NasserLaboratoire Biochimie, Faculté des Sciences et Techniques, Neurosciences, Ressources Naturelles et Environnement, Université Hassan I, BP577, 26000, Settat, Morocco.
Stéphane SavaryCentre des Sciences du Goût et de l'Alimentation (CSGA), CNRS, INRAe, Institut Agro, Université de Bourgogne Europe, 21000, Dijon, France.
Michel JadotPhysiological Chemistry Laboratory, URPhyM, NARILIS, University of Namur, Namur, Belgium.
Mustapha Cherkaoui-MalkiCentre des Sciences du Goût et de l'Alimentation (CSGA), CNRS, INRAe, Institut Agro, Université de Bourgogne Europe, 21000, Dijon, France. malki@u-bourgogne.fr.
Pierre AndreolettiCentre des Sciences du Goût et de l'Alimentation (CSGA), CNRS, INRAe, Institut Agro, Université de Bourgogne Europe, 21000, Dijon, France. Pierre.andreoletti@u-bourgogne.fr.

Funding

COST Action CA 16112Ministère de l'Enseignement et de la Recherche and the CNRST, 17UHP2019, MoroccoPHC Toubkal program TBK 19/92 n° n° Campus France: 41501RJProjet d'Envergure Neurosens 2022Y-14248
6 · The paper itself

Abstract

Peroxisomes have gained increasing attention and are now considered vital players in normal physiological functions. To gain further insight into how peroxisomal defects influence cellular functions, we developed BV-2 microglial models featuring CRISPR/Cas9 gene-edited mutations in peroxisomal Acox1 or Abcd1 and Abcd2 genes. The Acox1

Indexed as

Cell FractionationMicrogliaPeroxisomesAnimalsATP Binding Cassette Transporter, Subfamily DCell LineMiceOxidation-ReductionSubcellular FractionsATP Binding Cassette Transporter, Subfamily DABCD1ABCD2ACOX1BV-2 cellsCell fractionationMicrogliaNycodenz gradientPeroxisome

Identifiers

PMID40229507

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.