Evidence map›Paper›PMID 40229472›Full record

ReviewMikrochimica acta2025

Recent advances in microfluidic-based photoelectrochemical (PEC) sensing platforms for biomedical applications.

Zaman Abdalhussein Ibadi Alaridhee, Mohammed B Alqaraguly, Shoira Formanova, Rustamkhon Kuryazov, Morug Salih Mahdi, Waam Mohammed Taher, Mariem Alwan, Majid S Jabir, Faeza H Zankanah, Hasan Majdi and 3 more

Abstract readReview
PubMed Publisher
In one paragraph

Review in Mikrochimica acta, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. TiOMicromachines · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Zaman Abdalhussein Ibadi AlaridheeDepartment of Medical Laboratory Techniques, College of Health and Medical Techniques, University of Alkafeel, Najaf, Iraq.
Mohammed B AlqaragulyMedical Laboratories Techniques, Hilla University College, Babylon, Iraq.
Shoira FormanovaDepartment of Chemistry and Its Teaching Methods, Tashkent State Pedagogical University, Tashkent, Uzbekistan. formanova.sh@gmail.com.
Rustamkhon KuryazovUrgench State University, Kh. Olimjon St. 14, 220100, Urgench, Uzbekistan.
Morug Salih MahdiCollege of MLT, Ahl Al Bayt University, Karbala, Iraq.
Waam Mohammed TaherCollege of Nursing, National University of Science and Technology, Dhi Qar, Iraq.
Mariem AlwanPharmacy College, Al-Farahidi University, Baghdad, Iraq.
Majid S JabirDepartment of Applied Sciences, University of Technology, Baghdad, Iraq.
Faeza H ZankanahCollege of Health & Medical Technology, Uruk University, Baghdad, Iraq.
Hasan MajdiDepartment of Chemical Engineering and Petroleum Industries, Al-Mustaqbal University College, Babylon, 51001, Iraq.
Mahmod Jasem JawadDepartment of Pharmacy, Al-Zahrawi University College, Karbala, Iraq.
Atheer Khdyair HamadGilgamesh Ahliya University, Baghdad, Iraq.
Khurshed BozorovDepartment of Organic Synthesis and Bioorganic Chemistry, Institute of Biochemistry, Samarkand State University, University Blvd. 15, 140104, Samarkand, Uzbekistan. khurshedbek@gmail.com.

Funding

Alnoor University ANUI2024M111Organization of the Laboratory for the Creation of Anticancer Drugs ALM-202310062530
6 · The paper itself

Abstract

Photoelectrochemical (PEC) techniques seamlessly combine electrochemical and spectroscopic principles, offering a powerful platform for the detection of biomarkers and biological molecules in clinical and biomedical settings. This review provides a comprehensive overview of microfluidic PEC probes, emphasizing their potential for ultrasensitive detection through enhanced light absorption and charge transfer processes. Key advantages of microfluidic PEC include real-time monitoring of biological processes, non-invasive detection, and the possibility of multiplexing when integrated with various quantification modalities. However, the practical implementation of PEC faces challenges such as bulky setup, matrix interference, and stability of PEC-active materials. Also, this paper discusses the intricate mechanisms of PEC sensing, highlighting the roles of nanomaterials in enhancing microfluidic PEC systems. Additionally, the limitations inherent in PEC material selection, including stability and bandgap engineering, are critically discussed. Solutions such as doping and the development of composite materials are proposed to address these issues. Through presented examples of PEC applications in biomedical fields, this review elucidates the future potential of PEC-based methods as reliable and effective tools for diagnostic applications. Additionally, this review proposes the most effective probes for future investigations to develop commercial devices.

Indexed as

Biosensing TechniquesElectrochemical TechniquesMicrofluidic Analytical TechniquesBiomarkersHumansPhotochemical ProcessesBiomarkersBiomedical applicationMicrofluidicPhotoelectrochemicalPhotoelectrochemical materials

Identifiers

PMID40229472

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.