Evidence map›Paper›PMID 40229265›Full record

ReviewNature communications2025

Engineering biology applications for environmental solutions: potential and challenges.

David J Lea-Smith, Francis Hassard, Frederic Coulon, Natalie Partridge, Louise Horsfall, Kyle D J Parker, Robert D J Smith, Ronan R McCarthy, Boyd McKew, Tony Gutierrez and 5 more

Abstract readReview
In one paragraph

Review in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Beyond the Usual Suspects: EmergingInternational journal of molecular sciences · 2026
    Review
  5. Review
  6. Review
  7. Review
  8. COApplied microbiology and biotechnology · 2026
    Review
  9. Review
  10. Review
  11. Review
  12. Article
  13. Review
  14. Review
  15. Review
  16. Secure biosystems design inApplied and environmental microbiology · 2025
    Article
  17. Review
  18. Review
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

David J Lea-Smith *University of East Anglia, Norwich, UK. d.lea-smith@uea.ac.uk.ORCID http://orcid.org/0000-0003-2463-406X
Francis Hassard *Cranfield University, Cranfield, UK.ORCID http://orcid.org/0000-0003-4803-6523
Frederic CoulonCranfield University, Cranfield, UK.ORCID http://orcid.org/0000-0002-4384-3222
Natalie PartridgeGitLife Biotech Ltd, Newcastle Upon Tyne, UK.ORCID http://orcid.org/0009-0005-0991-5455
Louise HorsfallUniversity of Edinburgh, Edinburgh, UK.ORCID http://orcid.org/0000-0003-1594-2992
Kyle D J ParkerUniversity of Edinburgh, Edinburgh, UK.ORCID http://orcid.org/0009-0005-7174-4423
Robert D J SmithUniversity of Edinburgh, Edinburgh, UK.ORCID http://orcid.org/0000-0002-5814-6032
Ronan R McCarthyBrunel University London, Uxbridge, UK.ORCID http://orcid.org/0000-0002-7480-6352
Boyd McKewUniversity of Essex, Colchester, UK.
Tony GutierrezHeriot-Watt University, Edinburgh, UK.ORCID http://orcid.org/0000-0002-6127-8511
Vinod KumarCranfield University, Cranfield, UK.
Gabriella DotroCranfield University, Cranfield, UK.
Zhugen YangCranfield University, Cranfield, UK.ORCID http://orcid.org/0000-0003-4183-8160
EBIC partners
Natalio KrasnogorGitLife Biotech Ltd, Newcastle Upon Tyne, UK. natalio.krasnogor@newcastle.ac.uk.ORCID http://orcid.org/0000-0002-2651-4320

Funding

RCUK | Biotechnology and Biological Sciences Research Council (BBSRC) BB/S020365RCUK | Biotechnology and Biological Sciences Research Council (BBSRC) BB/Y008332/1
6 · The paper itself

Abstract

Engineering biology applies synthetic biology to address global environmental challenges like bioremediation, biosequestration, pollutant monitoring, and resource recovery. This perspective outlines innovations in engineering biology, its integration with other technologies (e.g., nanotechnology, IoT, AI), and commercial ventures leveraging these advancements. We also discuss commercialisation and scaling challenges, biosafety and biosecurity considerations including biocontainment strategies, social and political dimensions, and governance issues that must be addressed for successful real-world implementation. Finally, we highlight future perspectives and propose strategies to overcome existing hurdles, aiming to accelerate the adoption of engineering biology for environmental solutions.

Indexed as

BioengineeringSynthetic BiologyBiodegradation, EnvironmentalHumansNanotechnology

Identifiers

PMID40229265
PMCPMC11997111

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.