Evidence map›Paper›PMID 40228325›Full record

ArticleDrug and alcohol dependence2025

Clinical pharmacist practitioners prescribing of buprenorphine for opioid use disorder.

Jacob D Baylis, Terri L Jorgenson, Haley E Pals, Catherine S Hwang, Michelle D Colvard, Veldana Alliu, Tera Moore, Lewei A Lin, Jessica Wyse, Eric J Hawkins and 2 more

Abstract read
In one paragraph

Article in Drug and alcohol dependence, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Jacob D BaylisVulnerable Veteran Innovative Patient-aligned Care Team (VIP), Informatics, Decision-Enhancement and Analytic Sciences (IDEAS) Center, VA Salt Lake City Health Care System, Salt Lake City, UT, USA; Program for Addiction Research, Clinical Care, Knowledge, and Advocacy (PARCKA), Division of Epidemiology, Department of Internal Medicine, University of Utah School of Medicine, Salt Lake City, UT, USA.
Terri L JorgensonClinical Pharmacy Practice Office, Pharmacy Benefits Management, Veterans Health Administration, Department of Veterans Affairs, USA.
Haley E PalsTomah VA Medical Center, Tomah, WI, USA.
Catherine S HwangDivision of General Internal Medicine and Geriatrics, Oregon Health and Science University, Portland, OR, USA; Section of General Internal Medicine, VA Portland Health Care System, Portland, OR, USA.
Michelle D ColvardVA Tennessee Valley Healthcare System, Nashville, TN, USA.
Veldana AlliuClinical Pharmacy Practice Office, Pharmacy Benefits Management, Veterans Health Administration, Department of Veterans Affairs, USA.
Tera MooreClinical Pharmacy Practice Office, Pharmacy Benefits Management, Veterans Health Administration, Department of Veterans Affairs, USA.
Lewei A LinCenter for Clinical Management Research, VA Ann Arbor Healthcare System, USA; Department of Psychiatry, University of Michigan Medical School, Ann Arbor, MI, USA.
Jessica WyseCenter to Improve Veteran Involvement in Care (CIVIC), VA Portland Health Care System, Portland, OR, USA; School of Public Health, Oregon Health & Science University, Portland, OR, USA.
Eric J HawkinsCenter of Excellence in Substance Addiction Treatment and Education, VA Puget Sound Health Care System, Seattle, WA, USA; Health Services Research & Development (HSR&D) Seattle Center of Innovation for Veteran-Centered and Value-Driven Care, Veterans Affairs (VA) Puget Sound Health Care System, Seattle, WA, USA; Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle, WA, USA.
Hildi J HagedornCenter of Excellence in Substance Addiction Treatment and Education, VA Puget Sound Health Care System, Seattle, WA, USA; Center for Care Delivery & Outcomes Research, Minneapolis VA Healthcare System, Minneapolis, MN, USA; Department of Psychiatry & Behavioral Sciences, University of Minnesota, Minneapolis, MN, USA.
Adam J GordonVulnerable Veteran Innovative Patient-aligned Care Team (VIP), Informatics, Decision-Enhancement and Analytic Sciences (IDEAS) Center, VA Salt Lake City Health Care System, Salt Lake City, UT, USA; Program for Addiction Research, Clinical Care, Knowledge, and Advocacy (PARCKA), Division of Epidemiology, Department of Internal Medicine, University of Utah School of Medicine, Salt Lake City, UT, USA. Electronic address: adam.gordon@hsc.utah.edu.

Funding

Suicide Prediction and Prevention for People at Risk for Opioid Use DisorderUG1DA040316 · NIDA · HENNEPIN HEALTHCARE RESEARCH INSTITUTE · PI GAVIN BART · 2015 to 2026
$42.2M
Greater Intermountain Node (CTN-0151)UG1DA049444 · NIDA · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI Gerald T. Cochran, Gerald T. Cochran · 2019 to 2026
$16.8M
HSRD VA IK2 HX003007NIDA NIH HHS UG1 DA040316NIDA NIH HHS UG1 DA049444
6 · The paper itself

Abstract

backgroundClinical Pharmacist Practitioners (CPPs) have a long history of collaborating with other prescribers for the provision of buprenorphine medication treatment for opioid use disorder (B-MOUD). In January 2023, with the removal of the DATA 2000 X-waiver process, CPPs were allowed to prescribe B-MOUD in states that allow CPP prescriptive authority of controlled substances. We sought to examine CPP prescribing patterns of B-MOUD in a large heath care system in 2023.

methodsWe conducted a retrospective cohort study of patients with opioid use disorder (OUD) who received B-MOUD care in 2023 within the Veterans Health Administration (VHA). B-MOUD was defined as a formulation of buprenorphine indicated for OUD. We characterized Veterans who were prescribed B-MOUD by CPPs and examined the characteristics of these prescriptions and the episodes of care (EOC).

resultsIn 2023, 22,863 Veterans received B-MOUD; 1090 (4.8 %) from a CPP. Veterans prescribed B-MOUD by CPPs were primarily 36-50 years old (n = 419, 38.4 %), male (n = 987, 90.6 %), white (n = 987, 90.6 %), non-Hispanic/Latino (n = 1043, 95.7 %), and in urban areas (n = 648, 59.4 %). 110 CPPs prescribed B-MOUD in 36 states representing 1.9 % of all B-MOUD prescribers in 2023. CPPs prescribed 5258 B-MOUD prescriptions, conducted 339 (2.7 %) initiations, were involved in 1162 (4.2 %) of all EOC throughout the year, and were the sole prescriber for 16.6 % of EOC. CPP-involved EOC had 86.9 % (n = 867) 90-day retention.

conclusionWhen they were able to, VHA CPPs were early adopters in prescribing B-MOUD. B-MOUD prescribing by CPPs is an emerging opportunity to further expand access to B-MOUD.

Indexed as

BuprenorphineDrug PrescriptionsNarcotic AntagonistsOpiate Substitution TreatmentOpioid-Related DisordersPharmacistsPractice Patterns, Physicians'AdultFemaleHumansMaleMiddle AgedRetrospective StudiesUnited StatesUnited States Department of Veterans AffairsVeteransBuprenorphineNarcotic AntagonistsBuprenorphineClinicalOpioid-related disordersPharmacistsVeteransVeterans health services

Identifiers

PMID40228325
PMCPMC12491063

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.