SynthesisMedicine2025
Association of obstructive sleep apnea risk with allergic asthma: A systematic review and meta-analysis.
Synthesis in Medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Authors and funding
2 authors.
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Abstract
backgroundThere is a close relationship between asthma and obstructive sleep apnea (OSA), and the mechanisms of these 2 diseases are overlapped. However, the relationship between OSA and allergic asthma remains to be analyzed through systematic review and meta-analysis.
methodsA systematic search was conducted using Scopus, PubMed, ISI, Google Scholar, and Cochrane Library by utilizing the keywords Allergic asthma, Obstructive sleep apnea, and OSA. Hazard ratio, odds ratio (OR), and risk ratio with 95% confidence interval, fixed and Mantel-Haenszel methods were calculated. Statistical software Stata was used for the evaluation of this meta-analysis.
resultsFinally, 19 articles were included in this study. The prevalence of OSA in allergic asthma patients was 35.25% (19.92%, 50.57%), which was statistically significant, and pooled analysis of ORs observed in individual studies showed that the odds of OSA prevalence were 2.24 (1.32, 3.12) (P < 0.001). Also, the prevalence of OSA risk in allergic asthma patients was 30.08% (19.73%, 40.43%), which was statistically significant, and pooled analysis of ORs observed in individual studies showed that the odds of OSA risk were 3.46 (2.96, 4.94) (P < 0.001).
conclusionThe present meta-analysis showed that the prevalence of OSA as well as the OSA risk in patients with asthma were significantly higher compared with healthy people.
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