Evidence map›Paper›PMID 40228258›Full record

ArticleMedicine2025

A comparative study of limb load on the healthy side of above-knee amputees after reconstruction of assistive walking devices.

Lingjie Zeng, Yitian Wang, Minxun Lu, Yong Nie, Yong Zhou, Li Min, Xiangdong Zhu, Chongqi Tu

Abstract readComparative Study
In one paragraph

Article in Medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Lingjie ZengNational Engineering Research Center for Biomaterials, Sichuan University, Chengdu, China.ORCID 0009-0002-7058-936
Yitian WangDepartment of Orthopedics, West China Hospital, Sichuan University, Chengdu, China.
Minxun LuDepartment of Orthopedics, West China Hospital, Sichuan University, Chengdu, China.
Yong NieDepartment of Orthopedics, West China Hospital, Sichuan University, Chengdu, China.
Yong ZhouDepartment of Orthopedics, West China Hospital, Sichuan University, Chengdu, China.
Li MinDepartment of Orthopedics, West China Hospital, Sichuan University, Chengdu, China.
Xiangdong ZhuNational Engineering Research Center for Biomaterials, Sichuan University, Chengdu, China.
Chongqi TuDepartment of Orthopedics, West China Hospital, Sichuan University, Chengdu, China.

Funding

Sichuan Science and Technology Programs 2022YFG0109
6 · The paper itself

Abstract

Patients with above-knee amputations often experience postoperative secondary diseases in their unaffected leg, including reduced bone density, muscle atrophy, and osteoarthritis. These conditions arise due to altered limb load resulting from the amputation. Assistive walking devices offer additional support and can modify limb load. To assess the impact of different assistive devices on limb load in the unaffected leg, we conducted a study with 13 above-knee amputation patients and thirteen healthy individuals. Participants walked at a self-selected speed while using a prosthetic, single crutch, or double crutches. Gait analysis was performed using Qualisys motion capture and force plates, and kinematic and kinetic data were analyzed using custom OpenSim software. Our results indicate that the prosthetic group closely resembles the healthy group but exhibits differences in knee joint adduction moments and knee joint contact forces. Among the groups, the single-crutch group bears the highest load, while the double-crutches group has the lowest load, even lower than the healthy group. Bio-inspired prosthetics are recommended for long-term use, but optimizing kinematic symmetry through rehabilitation methods and prosthetic modifications is essential. Prolonged use of crutches should be minimized to reduce stress concentration, and resistance training is a suitable strategy.

Indexed as

Amputation, SurgicalAmputeesArtificial LimbsCrutchesWalkingAdultAgedBiomechanical PhenomenaFemaleGaitHumansKnee JointMaleMiddle AgedWeight-Bearingabove-knee amputeesassistive walking devicescomparative studylimb load

Identifiers

PMID40228258
PMCPMC11999410

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.