Evidence map›Paper›PMID 40228107›Full record

ArticleACS infectious diseases2025

A Photoactivatable Free Mycolic Acid Probe to Investigate Mycobacteria-Host Interactions.

Kingsley C Agu, Nicholas Banahene, Carolina Santamaria, Christi Y Kim, Jessica Cabral, Kyle J Biegas, Casey Papson, Andrew D Kruskamp, M Sloan Siegrist, Benjamin M Swarts

Abstract read
In one paragraph

Article in ACS infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Biofilm Associated Persistence and Drug Tolerance in Mycobacteria Within Host Microenvironments.APMIS : acta pathologica, microbiologica, et immunologica Scandinavica · 2026
    Review
  3. Review
  4. Trehalose dimycolate inhibits phagosome maturation and promotes intracellularProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Kingsley C AguDepartment of Chemistry and Biochemistry, Central Michigan University, Mount Pleasant, Michigan 48859, United States.
Nicholas BanaheneDepartment of Chemistry and Biochemistry, Central Michigan University, Mount Pleasant, Michigan 48859, United States.
Carolina SantamariaMolecular and Cellular Biology Program, University of Massachusetts, Amherst, Massachusetts 01003, United States.
Christi Y KimDepartment of Microbiology, University of Massachusetts, Amherst, Massachusetts 01003, United States.
Jessica CabralDepartment of Microbiology, University of Massachusetts, Amherst, Massachusetts 01003, United States.
Kyle J BiegasDepartment of Chemistry and Biochemistry, Central Michigan University, Mount Pleasant, Michigan 48859, United States.
Casey PapsonDepartment of Chemistry and Biochemistry, Central Michigan University, Mount Pleasant, Michigan 48859, United States.
Andrew D KruskampDepartment of Chemistry and Biochemistry, Central Michigan University, Mount Pleasant, Michigan 48859, United States.
M Sloan SiegristMolecular and Cellular Biology Program, University of Massachusetts, Amherst, Massachusetts 01003, United States.ORCID 0000-0002-8232-3246
Benjamin M SwartsDepartment of Chemistry and Biochemistry, Central Michigan University, Mount Pleasant, Michigan 48859, United States.ORCID 0000-0001-8402-359X

Funding

Host proteins that interact with the BCG cell envelopeR21AI163949 · NIAID · UNIVERSITY OF MASSACHUSETTS AMHERST · PI GRIMES, CATHERINE LEIMKUHLER, SIEGRIST, MARY SLOAN · 2021 to 2022
$432k
NIAID NIH HHS R21 AI163949
6 · The paper itself

Abstract

Mycolic acids are long-chain, α-branched, β-hydroxylated fatty acid lipids that populate the outer mycomembrane of mycobacteria, including the pathogen

Indexed as

Host-Pathogen InteractionsMolecular ProbesMycobacterium tuberculosisMycolic AcidsAnimalsHumansMacrophagesMiceReceptors, ImmunologicTuberculosisMolecular ProbesMycolic AcidsReceptors, Immunologicclick chemistryimmunologymacrophagesMycobacteriamycolic acidsouter membranephotoaffinitysynthesis

Identifiers

PMID40228107
PMCPMC12070411

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.