ArticleCirculation2025
Dose Response of Incidental Physical Activity Against Cardiovascular Events and Mortality.
Article in Circulation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- Testing a vigorous intermittent lifestyle physical activity intervention in adults transitioning to retirement: a pilot randomised controlled trial.Age and ageing · 2025Trial
- How a 10-minute bout requirement for physical activity affects guideline adherence estimates, Germany.Bulletin of the World Health Organization · 2026Article
- Intensity-specific physical activity and mortality in 147,414 adults: a pooled accelerometer analysis.The international journal of behavioral nutrition and physical activity · 2026Article
- Prospective Physical Activity, Sitting and Sleep consortium (ProPASS): addressing methodological and geographical barriers to inform global public health guidelines, interventions and precision medicine.British journal of sports medicine · 2026Article
- Unlocking the potential of light-intensity physical activity for public health: a call to action for research.British journal of sports medicine · 2026Article
- Effects of Lifestyle-Integrated Active Pursed-Lip Diaphragmatic Breathing Training on the Prognosis of Chronic Heart Failure: A Retrospective Real-World Study.Healthcare (Basel, Switzerland) · 2026Article
- Accelerometer-measured physical activity fragmentation and incident cardiovascular diseases: a prospective cohort study.Nutrition journal · 2026Article
- Impact of physical activity patterns on major adverse cardiovascular events in adults with hypertension.British journal of sports medicine · 2026Article
- Assessing Physicians' Knowledge, Attitudes, Intentions, Abilities, and Behaviour Toward Physical Activity and Exercise in Non-Communicable Diseases: Questionnaire Development Using an e-Delphi and Cross-Sectional Design.Healthcare (Basel, Switzerland) · 2026Article
- Physiology of lived experience: Cruising among the Swiss peaks.Experimental physiology · 2026Article
- OpenMetabolics: Estimating energy expenditure using a smartphone worn in a pocket.Communications engineering · 2026Article
- Vigorous intermittent lifestyle physical activity (VILPA) and mortality risk among US adults: a wearables-based national cohort study.The international journal of behavioral nutrition and physical activity · 2026Article
- From Daily Routines to Cardiovascular Health: The Untapped Potential of Incidental Physical Activity.Reviews in cardiovascular medicine · 2026Review
- Digital health solutions for chronic disease physical activity management: wearable devices, artificial intelligence, and public health implementation.Frontiers in public health · 2026Review
- Associations of Wearable-Measured Sleep and Physical Activity With Memory Performance in Older Adults: Cross-Sectional Study With Actigraphy and MRI.JMIR aging · 2025Observational
- Commentary on: Intensity modifies the association between continuous bouts of physical activity and risk of mortality: A prospective UK Biobank cohort analysis.Journal of sport and health science · 2025Article
- Associations of accelerometer-measured light-intensity physical activity with mortality and incidence of cardiovascular diseases and cancers: A prospective cohort study.Journal of sport and health science · 2025Article
- Open-source customizable website to follow-up physical rehabilitation of cardiovascular patients at home.Frontiers in cardiovascular medicine · 2025Article
Corrections and comments
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Authors and funding
15 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundFew middle-aged and older adults engage in regular leisure-time exercise. Incidental physical activity (IPA) encompasses activities of daily living outside the leisure-time domain. No dose-response study is available to guide IPA-focused interventions and guidelines. We examined the associations of device-assessed IPA intensities (vigorous [VIPA], moderate [MIPA], light [LIPA]) with major adverse cardiovascular events (MACE) and mortality, and we estimated the "health equivalence" of LIPA and MIPA against 1 minute of VIPA.
methodsA total of 24 139 nonexercisers from the 2013 to 2015 UK Biobank accelerometry substudy (56.2% women) with a mean±SD age of 61.9±7.6 years were analyzed using a prospective cohort design. IPA energy expenditure and daily durations of VIPA, MIPA, and LIPA were calculated with a validated machine learning-based intensity classifier. MACE included incident stroke, myocardial infarction, and heart failure; CVD death; CVD mortality; and all-cause mortality.
resultsAnalyses included 22 107 (MACE), 22 174 (CVD mortality), and 24 139 (all-cause mortality) participants, corresponding to 908/223/1071 events over 7.9 years of follow-up. IPA volume exhibited an L-shaped association with a nadir at ≈35 to 38 kJ·kg
conclusionsAny daily IPA amount of vigorous or moderate intensity was associated with lower CVD risk in a dose-response manner. LIPA had weak associations with all outcomes. One minute of vigorous or ≈3.0 to 3.5 minutes of moderate IPA was associated with a similar degree of lower CVD risk. Our findings highlight the potential cardiovascular health value of incidental physical activity, especially for people who struggle to do structured exercise.
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