Evidence map›Paper›PMID 40227828›Full record

ArticleCancers2025

Perioperative and Mid-Term Oncological and Functional Outcomes After Partial Nephrectomy for Entirely Endophytic Renal Tumors: A Prospective Multicenter Observational Study (The RECORD2 Project).

Fabrizio Di Maida, Andrea Mari, Daniele Amparore, Alessandro Antonelli, Riccardo Schiavina, Riccardo Giuseppe Bertolo, Alessandro Veccia, Eugenio Brunocilla, Riccardo Campi, Luigi Da Pozzo and 14 more

Abstract read
In one paragraph

Article in Cancers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Fabrizio Di MaidaUnit of Oncologic Minimally-Invasive Urology and Andrology, Department of Experimental and Clinical Medicine, University of Florence, Careggi Hospital, 50134 Florence, Italy.ORCID 0000-0003-1885-4808
Andrea MariUnit of Oncologic Minimally-Invasive Urology and Andrology, Department of Experimental and Clinical Medicine, University of Florence, Careggi Hospital, 50134 Florence, Italy.ORCID 0000-0001-9070-5706
Daniele AmparoreDivision of Urology, Department of Oncology, San Luigi Gonzaga Hospital, School of Medicine, Orbassano, 10043 Turin, Italy.
Alessandro AntonelliUrology Clinic, Department of Surgery, Dentistry, Paediatrics and Gynaecology, University of Verona, Azienda Ospedaliera Universitaria Integrata di Verona, 37126 Verona, Italy.ORCID 0000-0002-7455-8803
Riccardo SchiavinaDepartment of Urology, University of Bologna, 40126 Bologna, Italy.
Riccardo Giuseppe BertoloUrology Clinic, Department of Surgery, Dentistry, Paediatrics and Gynaecology, University of Verona, Azienda Ospedaliera Universitaria Integrata di Verona, 37126 Verona, Italy.ORCID 0000-0003-0260-4601
Alessandro VecciaUrology Clinic, Department of Surgery, Dentistry, Paediatrics and Gynaecology, University of Verona, Azienda Ospedaliera Universitaria Integrata di Verona, 37126 Verona, Italy.
Eugenio BrunocillaDepartment of Urology, University of Bologna, 40126 Bologna, Italy.
Riccardo CampiUnit of Urological Robotic Surgery and Renal Transplantation, Department of Experimental and Clinical Medicine, University of Florence, Careggi Hospital, 50134 Florence, Italy.ORCID 0000-0001-5237-0888
Luigi Da PozzoDepartment of Urology, Papa Giovanni XXIII Hospital, 24127 Bergamo, Italy.
Cristian FioriDivision of Urology, Department of Oncology, San Luigi Gonzaga Hospital, School of Medicine, Orbassano, 10043 Turin, Italy.
Paolo GonteroUrology Unit, Department of Surgical Sciences, University of Turin, 10124 Turin, Italy.
Antonio Andrea GrossoUnit of Oncologic Minimally-Invasive Urology and Andrology, Department of Experimental and Clinical Medicine, University of Florence, Careggi Hospital, 50134 Florence, Italy.ORCID 0000-0001-5973-789X
Luca LambertiniUnit of Oncologic Minimally-Invasive Urology and Andrology, Department of Experimental and Clinical Medicine, University of Florence, Careggi Hospital, 50134 Florence, Italy.
Nicola LongoDepartment of Urology, University Federico II of Naples, 80138 Naples, Italy.
Ciro ImbimboDepartment of Urology, University Federico II of Naples, 80138 Naples, Italy.
Alberto BrigantiUnit of Urology, Division of Experimental Oncology, Urological Research Institute (URI), IRCCS San Raffaele Scientific Institute, 20132 Milan, Italy.
Francesco MontorsiUnit of Urology, Division of Experimental Oncology, Urological Research Institute (URI), IRCCS San Raffaele Scientific Institute, 20132 Milan, Italy.
Francesco PorpigliaDivision of Urology, Department of Oncology, San Luigi Gonzaga Hospital, School of Medicine, Orbassano, 10043 Turin, Italy.
Luigi SchipsDepartment of Urology, SS Hospital. Annunziata, 66100 Chieti, Italy.
Nazareno SuardiDepartment of Urology, Ospedali Civili, University of Brescia, 25121 Brescia, Italy.
Sergio SerniDepartment of Experimental, Diagnostic, and Specialty Medicine, University of Bologna, 40126 Bologna, Italy.
Bernardo RoccoDepartment of Urology, ASST Santi Paolo e Carlo, 20146 Milan, Italy.
Andrea MinerviniUnit of Oncologic Minimally-Invasive Urology and Andrology, Department of Experimental and Clinical Medicine, University of Florence, Careggi Hospital, 50134 Florence, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

objectivesTotally endophytic renal tumors are a unique subset that pose significant technical challenges during partial nephrectomy (PN). The aim of this study was to evaluate the perioperative, oncologic, and functional outcomes of PN in this particular setting. MATERIALS AND

methodsWe retrospectively evaluated 4151 patients who had surgical treatment for renal tumors between January 2013 and December 2016 at 26 urological Italian Centers (RECORD 2 project). Only patients treated with PN for entirely endophytic renal tumor were considered for final analyses.

resultsA total of 211 patients were included, with a median PADUA score of 10 (IQR 9-11). Open, laparoscopic, and robotic approaches were used in 94 (44.5%), 52 (24.6%), and 65 (30.8%) cases, respectively. While surgical approach did not impact complication rates, robotic PN had significantly lower median blood loss (100 vs. 185 vs. 175 cc,

conclusionsThe conservative management of entirely endophytic renal tumors is associated with favorable functional and oncologic outcomes. Whenever technically feasible, conservative surgery should be prioritized to optimize early renal function recovery.

Indexed as

endophytic tumornephron-sparing surgerypartial nephrectomyrenal cell carcinomarobotics

Identifiers

PMID40227828
PMCPMC11987886

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.