Evidence map›Paper›PMID 40227784›Full record

ArticleCancers2025

Factors Affecting Psychosocial Distress in Adolescents and Young Adults with Cancer: BRIGHTLIGHT Cross-Sectional and Longitudinal Cohort Study Results.

Chana Korenblum, Rachel M Taylor, Lorna A Fern, Rachael Hough, Bethany Wickramasinghe

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. "I felt as though my life had come to an end": lived experiences of adolescents and young adults with cancer in Nepal.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  2. Article
  3. Article
  4. In their words: Experience of decision-making in adolescents with cancer - a qualitative meta-synthesis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Article
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Chana KorenblumThe Hospital for Sick Children, Princess Margaret Cancer Centre, Temerty Faculty of Medicine, University of Toronto, Toronto, ON M5G1X8, Canada.
Rachel M TaylorCentre for Nurse, Midwife and Allied Health Profession Led Research (CNMAR), University College London Hospitals NHS Foundation Trust, Department of Targeted Intervention, University College London, London NW1 2PG, UK.ORCID 0000-0002-0853-0925
Lorna A FernCancer Clinical Trials Unit, University College London Hospitals NHS Foundation Trust, London NW1 2PG, UK.ORCID 0000-0003-4821-8466
Rachael HoughChildren and Young Peoples Cancer Service, University College London Hospitals NHS Foundation Trust, Cancer Institute, University College London, London WC1E 6AG, UK.
Bethany WickramasingheDepartment of Targeted Intervention, University College London, London NW1 2PG, UK.ORCID 0009-0002-3855-0625

Funding

National Institute for Health Research RP-PG-1209-10013
6 · The paper itself

Abstract

BACKGROUND/

objectivesAYAs face unique psychosocial challenges compared to younger children and older adults. Little published data exists about symptoms of psychological distress in AYAs, particularly in large cohorts over time. This study aimed to (1) explore relationships between distress and variables known to impact mental health, (2) examine distress over time, and (3) consult with a patient and public involvement group (Young Advisory Panel, YAP) to contextualize the results.

methodsSecondary data analyses were conducted from a multicentre longitudinal cohort study, which recruited 830 participants aged 13-24 years newly diagnosed with different cancers. The mean age was 20.1 (SD 3.3) and 45% were female. Bespoke surveys, including a validated measure of psychosocial distress, were administered five times over 3 years following diagnosis. Participatory workshops were conducted with the YAP to gather their impressions of the study results and inform conclusions.

resultsAt the first time point, higher social support was associated with higher distress scores (β = 0.202,

conclusionsThis information identifies key targets, such as social support, that can inform the design of personalized screening and intervention tools. It also highlights specific timepoints at which these efforts can be directed to mitigate distress and improve quality of life. Future research should include longer-term follow-up, qualitative explorations of distress along the disease trajectory, and ongoing co-production efforts.

Indexed as

adolescentsanxietyBRIGHTLIGHTcancerdepressiondistressmental healthyoung adultyoung people

Identifiers

PMID40227784
PMCPMC11987992

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.