Evidence map›Paper›PMID 40227778›Full record

ArticleCancers2025

Inflammatory Fibroid Polyp (Vanek's Tumor): A Retrospective Multicentric Analysis of 67 Cases.

Mario Martín Sánchez, Víctor Domínguez-Prieto, Siyuan Qian Zhang, Hernán Darío Quiceno Arias, María Bernarda Álvarez Álvarez, Montiel Jiménez Fuertes, Cecilia Meliga, Santos Jiménez-Galanes, Héctor Guadalajara Labajo, Damián García Olmo and 1 more

Abstract read
In one paragraph

Article in Cancers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Mario Martín SánchezDepartment of Surgery, Fundación Jiménez Díaz University Hospital, Avenida de los Reyes Católicos 2, 28040 Madrid, Spain.ORCID 0000-0002-0186-1094
Víctor Domínguez-PrietoDepartment of Surgery, Fundación Jiménez Díaz University Hospital, Avenida de los Reyes Católicos 2, 28040 Madrid, Spain.ORCID 0000-0002-1354-5056
Siyuan Qian ZhangDepartment of Surgery, Fundación Jiménez Díaz University Hospital, Avenida de los Reyes Católicos 2, 28040 Madrid, Spain.ORCID 0000-0001-5497-1724
Hernán Darío Quiceno AriasDepartment of Pathology, Fundación Jiménez Díaz University Hospital, Avenida de los Reyes Católicos 2, 28040 Madrid, Spain.
María Bernarda Álvarez ÁlvarezDepartment of Pathology, Fundación Jiménez Díaz University Hospital, Avenida de los Reyes Católicos 2, 28040 Madrid, Spain.
Montiel Jiménez FuertesDepartment of Surgery, Fundación Jiménez Díaz University Hospital, Avenida de los Reyes Católicos 2, 28040 Madrid, Spain.
Cecilia MeligaDepartment of Surgery, Fundación Jiménez Díaz University Hospital, Avenida de los Reyes Católicos 2, 28040 Madrid, Spain.
Santos Jiménez-GalanesDepartment of Surgery, University Hospital Infanta Elena, 28342 Madrid, Spain.
Héctor Guadalajara LabajoDepartment of Surgery, Fundación Jiménez Díaz University Hospital, Avenida de los Reyes Católicos 2, 28040 Madrid, Spain.ORCID 0000-0001-6297-9347
Damián García OlmoDepartment of Surgery, Fundación Jiménez Díaz University Hospital, Avenida de los Reyes Católicos 2, 28040 Madrid, Spain.ORCID 0000-0002-9369-2338
Pedro Villarejo CamposDepartment of Surgery, Fundación Jiménez Díaz University Hospital, Avenida de los Reyes Católicos 2, 28040 Madrid, Spain.ORCID 0000-0002-1165-5593

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesInflammatory fibroid polyps, also known as Vanek's tumors, are rare benign lesions of the gastrointestinal tract. Although the exact cause remains unclear, several theories suggest an association with inflammatory processes and genetic factors. This study aims to present the largest cohort of inflammatory fibroid polyp cases to date, analyzing their clinical presentation, diagnostic methods, and treatment approaches. MATERIALS AND

methodsA retrospective multicentric analysis was conducted on 67 patients diagnosed with inflammatory fibroid polyps between 2013 and 2023 across four hospitals. Clinical data regarding tumor location, size, symptoms, and treatment were collected. Non-parametric statistical tests, including the chi-square test, Cramér's V coefficient, and the Mann-Whitney U test, were used to identify association between tumor characteristics, location, and treatment outcomes.

resultsThe cohort included 67 patients (58.2% female, median age 60 years). The stomach was the most common tumor site (47.8%), followed by the colon (32.8%), and small intestine (10.4%). The majority of patients (73.1%) were asymptomatic, while 9% experienced intestinal obstruction, all of which were located in the small intestine. Endoscopic resection was successful in 77.6% of cases, but surgical intervention was more frequently required for tumors in the small intestine. A significant association was found between larger tumor size, emergency presentation, intestinal location, and the need for surgery.

conclusionsInflammatory fibroid polyps are commonly managed with endoscopic resection, particularly in gastric and colonic locations. However, small intestinal tumors more often need surgical treatment, especially when presenting with complications like intestinal obstruction.

Indexed as

endoscopygastrointestinal submucosal tumorinflammatory fibroid polypintussusceptionsurgeryVanek’s tumor

Identifiers

PMID40227778
PMCPMC11987972

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.