Evidence map›Paper›PMID 40227632›Full record

ArticleCancers2025

A Pilot Study to Evaluate the Feasibility and Acceptability of a Tailored Multicomponent Rehabilitation Program for Adolescent and Young Adult (AYA) Cancer Survivors.

Lauren Corke, David M Langelier, Abha A Gupta, Scott Capozza, Eric Antonen, Gabrielle Trepanier, Lisa Avery, Christian Lopez, Beth Edwards, Jennifer M Jones

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cancers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Lauren CorkeCancer Rehabilitation and Survivorship Program, Princess Margaret Cancer Centre, Toronto, ON M5G 2C4, Canada.
David M LangelierDepartment of Clinical Neurosciences, Division on PM&R, University of Calgary, Calgary, AB T2N 1N4, Canada.ORCID 0000-0002-9863-5084
Abha A GuptaDivison of Hematology/Oncology, The Hospital for Sick Children, Toronto, ON M5G 1E8, Canada.
Scott CapozzaYale New Haven Health Outpatient Oncology Rehabilitation Services, Smilow Cancer Hospital Adult Cancer Survivorship Clinic, New Haven, CT 06519, USA.
Eric AntonenCancer Rehabilitation and Survivorship Program, Princess Margaret Cancer Centre, Toronto, ON M5G 2C4, Canada.
Gabrielle TrepanierTemerty Faculty of Medicine, University of Toronto, Toronto, ON M5S 3K3, Canada.ORCID 0000-0003-0050-0702
Lisa AveryDepartment of Biostatistics, Princess Margaret Cancer Centre, Toronto, ON M5G 2C4, Canada.
Christian LopezCancer Rehabilitation and Survivorship Program, Princess Margaret Cancer Centre, Toronto, ON M5G 2C4, Canada.ORCID 0000-0002-1496-7090
Beth EdwardsCancer Rehabilitation and Survivorship Program, Princess Margaret Cancer Centre, Toronto, ON M5G 2C4, Canada.
Jennifer M JonesCancer Rehabilitation and Survivorship Program, Princess Margaret Cancer Centre, Toronto, ON M5G 2C4, Canada.ORCID 0000-0002-8670-8514

Funding

Butterfield Chair in Cancer Survivorship Research and The Princess Margaret Cancer Foundation. N/A
6 · The paper itself

Abstract

backgroundAdolescent and young adult (AYA) cancer survivors have unique needs, yet few tailored rehabilitation programs exist. CaRE-AYA is an 8-week multidimensional rehabilitation program for AYAs that targets impairments, activity limitations and participation restrictions and comprises an individualized exercise prescription and weekly group-based exercise and self-management education.

methodsWe conducted a single-arm multi-method pragmatic feasibility study evaluating CaRE-AYA's feasibility, acceptability, and safety (primary outcomes) and assessed disability, physical functioning, mental health, and social functioning at baseline (T0), immediately post-intervention (T1), and 3 months post-intervention (T2).

resultsTwenty-five participants (median age: 32.8, 76% female) were enrolled. Participation (60%), retention (84% at T1, 72% at T2), and program adherence (76% for education classes, 74% for exercise classes) supported feasibility. Qualitative interviews (

conclusionsThe results suggest CaRE-AYA is feasible, acceptable, and safe. A randomized controlled trial is needed to determine the effectiveness.

Indexed as

adolescentscancer rehabilitationexerciseself-management skillssurvivorshipyoung adults

Identifiers

PMID40227632
PMCPMC11988022

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.