Evidence map›Paper›PMID 40227607›Full record

ArticleCancers2025

Ethnicity-Specific Molecular Alterations in MAPK and JAK/STAT Pathways in Early-Onset Colorectal Cancer.

Cecilia Monge, Brigette Waldrup, Francisco G Carranza, Enrique Velazquez-Villarreal

Abstract read
In one paragraph

Article in Cancers, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Cecilia MongeCenter for Cancer Research, National Cancer Institute, Bethesda, MD 20892, USA.ORCID 0000-0002-5558-2744
Brigette WaldrupCity of Hope, Beckman Research Institute, Department of Integrative Translational Sciences, Duarte, CA 91010, USA.ORCID 0009-0009-5991-9779
Francisco G CarranzaCity of Hope, Beckman Research Institute, Department of Integrative Translational Sciences, Duarte, CA 91010, USA.ORCID 0000-0003-1789-4197
Enrique Velazquez-VillarrealCity of Hope, Beckman Research Institute, Department of Integrative Translational Sciences, Duarte, CA 91010, USA.ORCID 0000-0002-3603-6414

Funding

Transgenic Mouse FacilityP30CA033572 · NCI · CITY OF HOPE/BECKMAN RESEARCH INSTITUTE · PI John Charles Williams · 1985 to 2026
$86.3M
USC PE-GCS: Optimizing Engagement of Hispanic Colorectal Cancer Patients in Cancer Genomic Characterization StudiesU2CCA252971 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI JOHN D. CARPTEN, HEINZ JOSEF LENZ · 2021 to 2026
$19.3M
Project 2U54CA285116 · NCI · BECKMAN RESEARCH INSTITUTE/CITY OF HOPE · PI ERNEST MARTINEZ, Victoria L. Seewaldt · 2023 to 2026
$6.8M
Research EducationU54CA285114 · NCI · UNIVERSITY OF CALIFORNIA RIVERSIDE · PI ERNEST MARTINEZ · 2023 to 2026
$6.2M
NCI NIH HHS NIH Award Number U54 CA285116NCI NIH HHS P30 CA033572NCI NIH HHS U2C CA252971NCI NIH HHS U54 CA285114NCI NIH HHS U54 CA285116NIH HHS 1P30CA033572-25A42
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

cancer disparitiesearly-onset colorectal cancergenetic mutationsJAK/STAT pathwayMAPK pathwayprecision medicine

Identifiers

PMID40227607
PMCPMC11988162

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.