Evidence map›Paper›PMID 40227605›Full record

ArticleNicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco2025

Menthol Characterizing Flavors in Cigarettes on Sale in England After a Characterizing Flavor Ban: Findings From Sensory and Chemical Assessments.

Debbie Robson, Christina N Kyriakos, Ann McNeill, Sophie Harrington, Michelle Page, Richard J O'Connor, John Robins, Maciej L Goniewicz

Abstract read
In one paragraph

Article in Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Debbie RobsonAddictions Department, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.
Christina N KyriakosDepartment of Psychiatry, Yale University School of Medicine, New Haven, CT, USA.
Ann McNeillAddictions Department, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.
Sophie HarringtonAddictions Department, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.
Michelle PageDepartment of Health Behavior, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA.ORCID 0000-0002-5962-8586
Richard J O'ConnorDepartment of Health Behavior, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA.
John RobinsAddictions Department, Institute of Psychiatry, Psychology & Neuroscience, King's College London, London, UK.
Maciej L GoniewiczDepartment of Health Behavior, Roswell Park Comprehensive Cancer Center, Buffalo, NY, USA.ORCID 0000-0001-6748-3068

Funding

Yale Center for the Study of Tobacco Product Use and Addiction (YCSTP) Project 2: Addictive Threshold of Nicotine and the Impact of SweetenersU54DA036151 · NIDA · YALE UNIVERSITY · PI LISA M FUCITO · 2018 to 2026
$41.6M
NIDA NIH HHSNIDA NIH HHS U54 DA036151
6 · The paper itself

Abstract

introductionIn May 2020, the United Kingdom banned menthol as a characteristic flavor in cigarettes. This study aimed to test cigarettes on sale in England in 2021-2022 for menthol and other characterizing flavors, through sensory and chemical testing. AIMS AND

methodsAssessments were conducted for 20 cigarette brands (16 tests and four reference products). An untrained consumer panel of 50 people who smoked daily were each randomized to smell one of the two blocks of 10 unburnt cigarettes in duplicate (50 assessments per product). Using the Check-All-That-Apply method, participants assessed the presence of 22 odor attributes, including menthol/mint. For each test and reference cigarette, proportions of assessments that identified menthol/mint, "fruity," "confectionary" and "non-tobacco" odors were identified and compared accounting for the within-participant duplicate testing. For each cigarette, the content of 34 flavoring chemicals (16 cooling/minty) was analyzed using gas chromatography-mass spectrometry.

resultsFour of the sixteen test cigarette products were more frequently identified by participants as having a menthol/mint odor than reference products and had detectable levels of menthol/mint in the chemical tests. For four other test products, there was some discordance between the chemical and sensory assessments. Sensory testing also identified a fruity odor in six test products and a confectionary odor in one test product. The compounds dihydroxyacetone and triacetin were detected above the LLOQ in all products.

conclusionsFour cigarette products for sale in England in 2021-2022 appeared non-compliant with the ban on menthol as a characterizing flavor in sensory and chemical tests. IMPLICATIONS: Menthol is known to enhance the appeal of tobacco products, particularly among young people. The subjective nature of determining "characterizing" flavors in tobacco products creates compliance challenges. Our findings suggest that more stringent regulatory policies around flavoring additives used in tobacco products might be necessary. An outright ban on menthol, other minty flavorings, and additives not essential to the manufacturing process could provide clearer guidelines for manufacturers and regulators.

Indexed as

CommerceFlavoring AgentsMentholTobacco ProductsAdultEnglandFemaleGas Chromatography-Mass SpectrometryHumansMaleMiddle AgedOdorantsTasteYoung AdultFlavoring AgentsMenthol

Identifiers

PMID40227605
PMCPMC12453683

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.