ArticleClinical oral investigations2025
Developmental defects of enamel and dental anomalies in children with skin diseases.
Article in Clinical oral investigations, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Enamel pits and enamel developmental defects in tuberous sclerosis complex: A descriptive synthesis and pooled prevalence analysis.Medicina oral, patologia oral y cirugia bucal · 2026Pooled it
- Oral Manifestations in Adolescents with Genetic Syndromes: A Retrospective Cross-Sectional Study.Journal of clinical medicine · 2025Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThe ectodermal origin of enamel and skin suggests a potential link between dermatological conditions and dental anomalies. This study aimed to evaluate the prevalence of developmental defects of enamel (DDE) and other dental anomalies in pediatric patients with skin diseases. MATERIALS AND
methodsThis cross-sectional study included 71 pediatric patients (aged 4-14) diagnosed with chronic skin diseases or genodermatoses, along with 41 age- and sex-matched controls. Enamel defects were assessed using both the Modified DDE Index and the Molar-Incisor Hypomineralization (MIH) Index, while panoramic radiographs were analyzed for hypodontia, taurodontism, short root anomaly, and primary failure of eruption.
resultsDDE-not-related MIH was significantly higher in the study group (p = 0.01). Additionally, other dental anomalies were significantly more prevalent in the study group (p = 0.03), particularly among patients with genodermatoses (p < 0.001). Ectodermal dysplasia and epidermolysis bullosa exhibited the highest prevalence of dental anomalies.
conclusionOur findings suggest a possible association between skin diseases, particularly genodermatoses, and an increased prevalence of dental anomalies. These results highlight the importance of early dental screening and multidisciplinary care for children with dermatological conditions. CLINICAL RELEVANCE: Understanding the dental implications of skin diseases can aid clinicians in early diagnosis and preventive strategies, improving oral health outcomes for affected children.
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