Evidence map›Paper›PMID 40227427›Full record

ArticleClinical research in cardiology : official journal of the German Cardiac Society2025

Transcatheter edge-to-edge repair in anatomically complex degenerative mitral regurgitation: 3-year outcomes from a real-world registry.

Nicoleta Nita, Michael Paukovitsch, Dominik Felbel, Matthias Gröger, Dominik Buckert, Mirjam Keßler, Wolfgang Rottbauer

Abstract read
In one paragraph

Article in Clinical research in cardiology : official journal of the German Cardiac Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Nicoleta NitaDepartment of Internal Medicine II, University Medical Center, 89081, Ulm, Germany. nicoleta.nita@uniklinik-ulm.de.
Michael PaukovitschDepartment of Internal Medicine II, University Medical Center, 89081, Ulm, Germany.
Dominik FelbelDepartment of Internal Medicine II, University Medical Center, 89081, Ulm, Germany.
Matthias GrögerDepartment of Internal Medicine II, University Medical Center, 89081, Ulm, Germany.
Dominik BuckertDepartment of Internal Medicine II, University Medical Center, 89081, Ulm, Germany.
Mirjam KeßlerDepartment of Internal Medicine II, University Medical Center, 89081, Ulm, Germany.
Wolfgang RottbauerDepartment of Internal Medicine II, University Medical Center, 89081, Ulm, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundRecent developments in transcatheter mitral valve repair (M-TEER) have expanded the indication for the procedure beyond conventional criteria to include patients with anatomically complex degenerative mitral regurgitation (DMR), but long-term outcomes are not well known.

aimsTo investigate outcomes by specific anatomical criteria in patients with severe DMR and complex valve anatomy enrolled in the prospective MitraUlm registry.

methodsClinical and echocardiographic 3-year outcomes of 304 patients with DMR and complex mitral valve anatomy, defined according to the CLASP IID registry criteria, were investigated. Outcomes were analysed separately for specific anatomical complexities.

results33.5% of patients had ≥ independent significant jets, 12% multisegmental prolapse, 12.3% mitral valve orifice area < 4 cm

conclusionsIn patients with anatomically complex DMR, advances in procedural techniques for M-TEER have allowed successful treatment with sustained MR reduction and improved long-term survival.

Indexed as

Cardiac CatheterizationHeart Valve Prosthesis ImplantationMitral ValveMitral Valve InsufficiencyRegistriesAgedAged, 80 and overEchocardiography, TransesophagealFemaleFollow-Up StudiesHumansMaleProspective StudiesSeverity of Illness IndexTime FactorsTreatment OutcomeCommissure regurgitationComplex mitral anatomyDegenerative mitral regurgitationMitral gradientMitral prolapseM-TEER

Identifiers

PMID40227427
PMCPMC12202683

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.